Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 13/20 | 0.48 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17955664 | 0.81 | CD274 (0.46) | CD274PDCD1 | |
| SCHEMBL12292164 | 0.80 | CD274 (0.49) | CD274PDCD1 | |
| SCHEMBL13114968 | 0.77 | CD274 (0.48) | CD274PDCD1 | |
| SCHEMBL17689591 | 0.76 | NQO1 (0.42) | — | |
| SCHEMBL21442861 | 0.75 | PTPN1 (0.40) | CD274PDCD1 | |
| SCHEMBL29292637 | 0.72 | CD274 (0.40) | CD274PDCD1 | |
| SCHEMBL3188344 | 0.72 | CYP1A2 (0.55) | CD274PDCD1 | |
| SCHEMBL13114964 | 0.72 | PTPN1 (0.53) | CD274 | |
| SCHEMBL9781302 | 0.71 | KMT2A (0.55) | — | |
| SCHEMBL21600930 | 0.70 | LMNA (0.38) | CD274ADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9405885-B2 | Drug discovery method | Keddem Bioscience Ltd. (IL) | 2016-08-02 | — | — | US | disclosed |
| US-20110237458-A1 | DRUG DISCOVERY METHOD | Keddem Bioscience Ltd. (IL) | 2011-09-29 | — | — | US | disclosed |
| US-20110237458-A1 | DRUG DISCOVERY METHOD | Keddem Bioscience Ltd. (IL) | 2011-09-29 | — | — | US | disclosed |