Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.40 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.40 |
| ▸ | ENPP3 | O14638 | 2/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29745666 | 0.74 | NPC1 (0.69) | GPR174NPC1HPGDHTTLMNA | |
| SCHEMBL15067758 | 0.74 | NPC1 (0.69) | GPR174NPC1HPGDHTTLMNA | |
| SCHEMBL28315134 | 0.66 | MET (0.65) | CA1CA2CA9CCNT1CDK2 | |
| SCHEMBL30286312 | 0.66 | MET (0.65) | CA1CA2CA9CCNT1CDK2 | |
| SCHEMBL31193469 | 0.66 | EGFR (0.61) | NPC1HPGDNPSR1CDK1CCNB1 | |
| SCHEMBL28315195 | 0.66 | CA1 (0.56) | HTTLMNACA12CA1CA2 | |
| SCHEMBL31088267 | 0.66 | CA1 (0.56) | HTTLMNACA12CA1CA2 | |
| SCHEMBL2037022 | 0.63 | DHODH (0.57) | NPC1HTTARTTBK1TTBK2 | |
| SCHEMBL29778738 | 0.63 | MPO (0.50) | CA12CA1CA2CA9CDK2 | |
| SCHEMBL28040105 | 0.63 | EGFR (0.65) | CA12CA1CA2CA9ENPP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011019634-A2 | ARYL SUBSTITUTED SULFONAMIDE COMPOUNDS AND THEIR USE AS ANTICANCER AGENTS | TAIPEI MEDICAL UNIVERSITY (TW) | 2011-02-17 | — | — | WO | disclosed |