Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | COXFA4 | O00483 | 1/20 | 0.43 |
| ▸ | ODC1 | P11926 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 8/20 | 0.40 |
| ▸ | EPAS1 | Q99814 | 4/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12315572 | 0.94 | COXFA4 (0.48) | COXFA4ODC1HIF1AEPAS1HSP90AA1 | |
| SCHEMBL14666104 | 0.90 | HIF1A (0.42) | COXFA4HIF1AEPAS1 | |
| SCHEMBL3458345 | 0.84 | COXFA4 (0.51) | COXFA4ODC1HIF1AEPAS1HSP90AA1 | |
| SCHEMBL14665999 | 0.82 | HIF1A (0.38) | COXFA4HIF1AEPAS1HSP90AA1 | |
| SCHEMBL13071314 | 0.79 | ALDH1A1 (0.38) | COXFA4HIF1AEPAS1 | |
| SCHEMBL12338065 | 0.79 | COXFA4 (0.48) | COXFA4ODC1HIF1AEPAS1HSP90AA1 | |
| SCHEMBL3456780 | 0.77 | COXFA4 (0.43) | COXFA4ODC1HIF1AEPAS1HSP90AA1 | |
| SCHEMBL12315598 | 0.77 | COXFA4 (0.52) | COXFA4ODC1HIF1AEPAS1HSP90AA1 | |
| SCHEMBL14666128 | 0.76 | COXFA4 (0.58) | COXFA4ODC1HIF1AEPAS1HSP90AA1 | |
| SCHEMBL12315465 | 0.76 | HIF1A (0.35) | HIF1AEPAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8263042-B2 | Contrast agents for myocardial perfusion imaging | LANTHEUS MEDICAL IMAGING, INC. (US) | 2012-09-11 | — | — | US | disclosed |