Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | COXFA4 | O00483 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 12/20 | 0.41 |
| ▸ | EPAS1 | Q99814 | 5/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14666128 | 0.91 | COXFA4 (0.58) | COXFA4HIF1AEPAS1HSP90AA1 | |
| SCHEMBL12315466 | 0.82 | COXFA4 (0.46) | COXFA4HIF1AEPAS1 | |
| SCHEMBL14666131 | 0.81 | HIF1A (0.54) | COXFA4HIF1AEPAS1HSP90AA1 | |
| SCHEMBL12315602 | 0.79 | COXFA4 (0.84) | COXFA4HIF1AEPAS1HSP90AA1 | |
| SCHEMBL14098880 | 0.77 | COXFA4 (0.61) | COXFA4HIF1AEPAS1HSP90AA1 | |
| SCHEMBL14666104 | 0.74 | HIF1A (0.42) | COXFA4HIF1AEPAS1 | |
| SCHEMBL11398330 | 0.74 | COXFA4 (0.62) | COXFA4HIF1AEPAS1 | |
| SCHEMBL12315553 | 0.73 | COXFA4 (0.62) | COXFA4HIF1AEPAS1HSP90AA1 | |
| SCHEMBL14098884 | 0.72 | COXFA4 (0.56) | COXFA4HIF1AEPAS1HSP90AA1 | |
| SCHEMBL16865512 | 0.72 | HIF1A (0.57) | COXFA4HIF1AEPAS1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8263042-B2 | Contrast agents for myocardial perfusion imaging | LANTHEUS MEDICAL IMAGING, INC. (US) | 2012-09-11 | — | — | US | disclosed |