Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | COXFA4 | O00483 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 13/20 | 0.35 |
| ▸ | EPAS1 | Q99814 | 9/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12315466 | 0.81 | COXFA4 (0.46) | COXFA4HIF1AEPAS1ALDH1A1CYP3A4 | |
| SCHEMBL12315472 | 0.80 | HIF1A (0.44) | COXFA4HIF1AEPAS1ALDH1A1CYP3A4 | |
| SCHEMBL12315608 | 0.80 | HIF1A (0.44) | COXFA4HIF1AEPAS1ALDH1A1CYP3A4 | |
| SCHEMBL12315469 | 0.73 | COXFA4 (0.66) | COXFA4HIF1AEPAS1ALDH1A1TDP1 | |
| SCHEMBL12315465 | 0.73 | HIF1A (0.35) | HIF1AEPAS1ALDH1A1HPGD | |
| SCHEMBL13071766 | 0.72 | PTGS1 (0.40) | COXFA4HIF1AALDH1A1ACHEBACE1 | |
| SCHEMBL12315468 | 0.72 | PTGS1 (0.40) | COXFA4HIF1AALDH1A1ACHEBACE1 | |
| SCHEMBL9581577 | 0.71 | ALDH1A1 (0.43) | COXFA4HIF1AEPAS1ALDH1A1CYP3A4 | |
| SCHEMBL7766618 | 0.69 | COXFA4 (0.49) | COXFA4HIF1AEPAS1ALDH1A1CYP3A4 | |
| SCHEMBL8066269 | 0.69 | COXFA4 (0.53) | COXFA4HIF1AEPAS1ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8263042-B2 | Contrast agents for myocardial perfusion imaging | LANTHEUS MEDICAL IMAGING, INC. (US) | 2012-09-11 | — | — | US | disclosed |