Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 4/20 | 0.34 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.34 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.34 |
| ▸ | TLR2 | O60603 | 3/20 | 0.33 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12914841 | 0.92 | LPAR1 (0.39) | LPAR1LPAR3PLA2G2CTLR2LPAR2 | |
| SCHEMBL14329141 | 0.89 | — | — | |
| SCHEMBL19543437 | 0.84 | — | — | |
| SCHEMBL13155378 | 0.81 | LPAR1 (0.36) | LPAR1LPAR3LPAR2 | |
| SCHEMBL12317193 | 0.80 | LPAR1 (0.32) | LPAR1LPAR3PLA2G2CTLR2 | |
| SCHEMBL25869902 | 0.74 | LPAR1 (0.47) | LPAR1LPAR3PLA2G2CTLR2LPAR2 | |
| SCHEMBL13155260 | 0.74 | LPAR1 (0.32) | LPAR1LPAR3 | |
| SCHEMBL17418170 | 0.71 | AKR1B1 (0.46) | TLR2 | |
| SCHEMBL21733117 | 0.71 | HSD17B10 (0.35) | — | |
| SCHEMBL31380117 | 0.71 | HSD17B10 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8263063-B2 | Multimeric VLA-4 antagonists comprising polymer moieties | ELAN PHARMACEUTICALS, INC. (US) | 2012-09-11 | — | — | US | disclosed |