Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 4/20 | 0.39 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.39 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.39 |
| ▸ | TLR2 | O60603 | 5/20 | 0.37 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 3/20 | 0.32 |
| ▸ | PPARD | Q03181 | 3/20 | 0.32 |
| ▸ | PPARA | Q07869 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12317240 | 0.92 | LPAR1 (0.34) | LPAR1LPAR3PLA2G2CTLR2LPAR2 | |
| SCHEMBL12317193 | 0.87 | LPAR1 (0.32) | LPAR1LPAR3PLA2G2CTLR2 | |
| SCHEMBL25869902 | 0.81 | LPAR1 (0.47) | LPAR1LPAR3PLA2G2CTLR2LPAR2 | |
| SCHEMBL14329141 | 0.80 | — | — | |
| SCHEMBL17418170 | 0.77 | AKR1B1 (0.46) | TLR2PLA2G4BAKR1B1PPARGPPARD | |
| SCHEMBL11307106 | 0.76 | LPAR1 (0.58) | LPAR1LPAR3PLA2G2CTLR2LPAR2 | |
| SCHEMBL21935885 | 0.75 | LPAR1 (0.35) | LPAR1LPAR3PLA2G2CTLR2LPAR2 | |
| SCHEMBL16473876 | 0.75 | HSD17B10 (0.44) | LPAR1LPAR3TLR2LPAR2CYP3A4 | |
| SCHEMBL30864421 | 0.74 | AKR1B1 (0.54) | PLA2G2CTLR2PLA2G4BAKR1B1HTT | |
| SCHEMBL12640102 | 0.74 | FFAR4 (0.49) | PLA2G2CTLR2PLA2G4BAKR1B1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120329807-A1 | Multimeric VLA-4 Antagonists Comprising Polymers Moieties | ELAN PHARMACEUTICALS, INC. (US) | 2012-12-27 | — | — | US | disclosed |
| US-20110002876-A1 | Multimeric VLA-4 Antagonists Comprising Polymer Moieties | ELAN PHARMACEUTICALS, INC. | 2011-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110002876-A1 | Multimeric VLA-4 Antagonists Comprising Polymer Moieties | VCAM1, ICAM1, ITGB4 | LPAR1 150/4885LPAR3 146/4885PLA2G2C 1631/4885 |
| US-20120329807-A1 | Multimeric VLA-4 Antagonists Comprising Polymers Moieties | VCAM1, ICAM1, ITGB4 | LPAR1 156/4885LPAR3 149/4885PLA2G2C 1614/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.