Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 4/20 | 0.36 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13155260 | 0.91 | LPAR1 (0.32) | LPAR1LPAR3 | |
| SCHEMBL16473876 | 0.85 | HSD17B10 (0.44) | LPAR1LPAR3HSD17B10LPAR2TDP1 | |
| SCHEMBL23408864 | 0.83 | HSD17B10 (0.46) | LPAR1LPAR3HSD17B10LPAR2TDP1 | |
| SCHEMBL12317240 | 0.81 | LPAR1 (0.34) | LPAR1LPAR3LPAR2 | |
| SCHEMBL4397692 | 0.81 | — | — | |
| SCHEMBL4396233 | 0.81 | CYP3A4 (0.33) | HSD17B10 | |
| SCHEMBL5401232 | 0.81 | CYP3A4 (0.33) | HSD17B10 | |
| SCHEMBL20089588 | 0.80 | HSD17B10 (0.40) | LPAR1LPAR3HSD17B10LPAR2TDP1 | |
| SCHEMBL24208086 | 0.77 | LPAR1 (0.49) | LPAR1LPAR3LPAR2 | |
| SCHEMBL19543437 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7794700-B2 | Multimeric VLA-4 antagonists comprising polymer moieties | ELAN PHARMACEUTICALS INC. (US) | 2010-09-14 | — | — | US | disclosed |