Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 8/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | GLS | O94925 | 1/20 | 0.49 |
| ▸ | HEXA | P06865 | 1/20 | 0.47 |
| ▸ | HEXB | P07686 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10126593 | 1.00 | GAA (0.51) | GAAHPGDNPSR1RAB9ANPC1 | |
| SCHEMBL11957411 | 0.98 | HPGD (0.53) | GAAHPGDNPSR1RAB9ANPC1 | |
| SCHEMBL8862746 | 0.91 | GAA (0.60) | GAAHPGDNPSR1RAB9ANPC1 | |
| SCHEMBL8862856 | 0.91 | GAA (0.60) | GAAHPGDNPSR1RAB9ANPC1 | |
| SCHEMBL7519591 | 0.91 | GAA (0.60) | GAAHPGDNPSR1RAB9ANPC1 | |
| SCHEMBL8862940 | 0.91 | GAA (0.60) | GAAHPGDNPSR1RAB9ANPC1 | |
| SCHEMBL2743018 | 0.89 | HPGD (0.61) | GAAHPGDNPSR1RAB9ANPC1 | |
| SCHEMBL25042416 | 0.86 | RAB9A (0.54) | GAAHPGDNPSR1RAB9ANPC1 | |
| SCHEMBL30274343 | 0.86 | RAB9A (0.54) | GAAHPGDNPSR1RAB9ANPC1 | |
| Fluoride SCHEMBL29965325 | 0.85 | RAB9A (0.53) | GAAHPGDNPSR1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2455457-B1 | Covalent tethering of functional groups to proteins | PROMEGA CORP (US) | 2015-03-11 | — | — | EP | disclosed |
| EP-2369006-A1 | Covalent tethering of functional groups to proteins | Promega Corporation (US) | 2011-09-28 | — | — | EP | disclosed |