Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | GLS | O94925 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25042416 | 1.00 | RAB9A (0.54) | RAB9ANPC1GAAHPGDNPSR1 | |
| Fluoride SCHEMBL29965325 | 0.98 | RAB9A (0.53) | RAB9ANPC1GAAHPGDNPSR1 | |
| SCHEMBL8862940 | 0.91 | GAA (0.60) | RAB9ANPC1GAAHPGDNPSR1 | |
| SCHEMBL8862746 | 0.91 | GAA (0.60) | RAB9ANPC1GAAHPGDNPSR1 | |
| SCHEMBL8862856 | 0.91 | GAA (0.60) | RAB9ANPC1GAAHPGDNPSR1 | |
| SCHEMBL7519591 | 0.91 | GAA (0.60) | RAB9ANPC1GAAHPGDNPSR1 | |
| SCHEMBL2743018 | 0.89 | HPGD (0.61) | RAB9ANPC1GAAHPGDNPSR1 | |
| SCHEMBL5371487 | 0.86 | SMN1; SMN2 (0.54) | RAB9ANPC1GAAHPGDNPSR1 | |
| SCHEMBL12317642 | 0.86 | GAA (0.51) | RAB9ANPC1GAAHPGDNPSR1 | |
| SCHEMBL230525 | 0.86 | SMN1; SMN2 (0.54) | RAB9ANPC1GAAHPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240336642-A1 | INHIBITORS OF 12/15-LIPOXYGENASE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2024-10-10 | — | — | US | disclosed |
| CN-118382435-A | 12/15-Lipoxygenase inhibitors | 总医院公司 | 2024-07-23 | — | — | CN | disclosed |
| EP-4384161-A1 | INHIBITORS OF 12/15-LIPOXYGENASE | The General Hospital Corporation (US) | 2024-06-19 | — | — | EP | disclosed |
| WO-2023019090-A1 | INHIBITORS OF 12/15-LIPOXYGENASE | THE GENERAL HOSPITAL CORPORATION (US) | 2023-02-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240336642-A1 | INHIBITORS OF 12/15-LIPOXYGENASE | ALOX15, LOX, ALOX12 | RAB9A 4139/4885NPC1 2167/4885GAA 647/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.