Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 2/20 | 0.36 |
| ▸ | BCR | P11274 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12323364 | 0.77 | MAPT (0.49) | MAPTALDH1A1HSD17B10KMT2AHPGD | |
| SCHEMBL12323830 | 0.77 | MAPT (0.49) | MAPTALDH1A1HSD17B10KMT2AHPGD | |
| SCHEMBL5936890 | 0.76 | ALDH1A1 (0.64) | MAPTALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL15223583 | 0.76 | ALDH1A1 (0.64) | MAPTALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL5936773 | 0.75 | ALDH1A1 (0.60) | MAPTALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL1688454 | 0.74 | ALDH1A1 (0.58) | MAPTALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL3670859 | 0.74 | GAA (0.42) | MAPTALDH1A1HPGDKDM4EUSP2 | |
| SCHEMBL2075063 | 0.73 | MTOR (0.55) | MAPTALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL12323369 | 0.72 | DDB1 (0.39) | MAPTALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL14940925 | 0.72 | MAPT (0.39) | MAPTALDH1A1HSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011113293-A1 | DIHYDROPTERIDINONE DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL USE THEREOF | 江苏恒瑞医药股份有限公司 (CN) | 2011-09-22 | — | — | WO | disclosed |