Sanguinarium

Sanguinarium

SCHEMBL123241

C[n+]1cc2c3c(ccc2c2ccc4cc5c(cc4c21)OCO5)OCO3

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BAD Q92934 7/20 1.00
ALDH1A1 P00352 6/20 1.00
MAPT P10636 6/20 1.00
HPGD P15428 6/20 1.00
SMN1; SMN2 Q16637 6/20 1.00
MAPK1 P28482 5/20 1.00
KMT2A Q03164 5/20 1.00
KDM4E B2RXH2 4/20 1.00
MEN1 O00255 4/20 1.00
LMNA P02545 4/20 1.00
ACHE P22303 4/20 1.00
TP53 P04637 3/20 1.00
CYP3A4 P08684 3/20 1.00
ALOX15 P16050 3/20 1.00
ALOX12 P18054 3/20 1.00
HSD17B10 Q99714 3/20 1.00
BCHE P06276 3/20 1.00
RGS17 Q9UGC6 2/20 1.00
RGS12 O14924 2/20 1.00
NPC1 O15118 2/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sanguinarium SCHEMBL30153784 1.00 BAD (1.00) BADALDH1A1MAPTHPGDSMN1; SMN2
Sanguinarium SCHEMBL23524622 1.00 BAD (1.00) BADALDH1A1MAPTHPGDSMN1; SMN2
Sanguinarium SCHEMBL30129850 1.00 BAD (1.00) BADALDH1A1MAPTHPGDSMN1; SMN2
Sanguinarium SCHEMBL29385229 1.00 BAD (1.00) BADALDH1A1MAPTHPGDSMN1; SMN2
Sanguinarium SCHEMBL8584009 0.99 BAD (0.97) BADALDH1A1MAPTHPGDSMN1; SMN2
Sanguinarium SCHEMBL43290 0.99 RAC1 (1.00) BADALDH1A1MAPTHPGDSMN1; SMN2
Sanguinarium SCHEMBL30668087 0.99 RAC1 (1.00) BADALDH1A1MAPTHPGDSMN1; SMN2
Sanguinarium SCHEMBL8937106 0.99 BAD (0.97) BADALDH1A1MAPTHPGDSMN1; SMN2
Sanguinarium SCHEMBL3222766 0.97 RAC1 (0.97) BADALDH1A1MAPTHPGDSMN1; SMN2
Sanguinarium SCHEMBL8583232 0.97 RAC1 (0.97) BADALDH1A1MAPTHPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 10482 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116655582-B Synthesis method and application of sanguinarine intermediate compound bromo-compound 宁波九胜创新医药科技有限公司 2026-05-12 CN claimed
EP-4687859-A2 DESMOPRESSIN ORAL COMPOSITIONS TULEX PHARMACEUTICALS, INC. (US) 2026-02-11 EP claimed
US-12544332-B2 Lipid vesicle compositions with penetration enhancing agents DDS RESEARCH INC. (CA) 2026-02-10 US claimed
US-12527764-B2 Methods and compositions for treating androgen receptor deficient, androgen receptor low, and castration-resistant prostate cancers FRED HUTCHINSON CANCER CENTER (US) 2026-01-20 US claimed
US-20250388939-A1 RECOMBINANT HOST CELLS WITH IMPROVED PRODUCTION OF L-DOPA, DOPAMINE, S-NOROCLAURINE OR DERIVATIVES THEREOF RIVER STONE BIOTECH APS (DK) 2025-12-25 US claimed
US-20250366479-A1 Non-Aqueous Organo Liquid Delivery Systems containing dispersed Organo Polycarboxylate Functionalities that improves efficiencies and properties of nitrogen sources SOILGENIC TECH LLC (US) 2025-12-04 US claimed
EP-3060043-B1 PESTICIDAL COMPOSITIONS AND RELATED METHODS CORTEVA AGRISCIENCE LLC (US) 2025-11-26 EP claimed
US-12471599-B2 Agricultural compositions comprising remodeled nitrogen fixing microbes PIVOT BIO, INC. (US) 2025-11-18 US claimed
EP-3578542-B1 COMPOSITIONS HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-11-12 EP claimed
WO-2025230540-A1 IMPROVED TREATMENT OF BREAST AND OTHER CANCERS USING ZINC CHLORIDE INSTEAD OF RADIATION BROOKS NORMAN ASHER (US) 2025-11-06 WO claimed
EP-0297535-A2 Drug delivery devices VIPONT PHARMACEUTICAL, INC. (US) 1989-01-04 EP claimed
US-4769452-A Production of purity benzo-c-phenanthridine alkaloid salts VIPONT LABORATORIES, INC. (US) 1988-09-06 US claimed
US-4767861-A Recovery of benzo-c-phenanthridine alkaloids VIPONT LABORATORIES (US) 1988-08-30 US claimed
US-4735945-A Method for inhibiting bone resorption and collagenase release VIPONT LABORATORIES, INC. (US) 1988-04-05 US claimed
US-4683133-A PUMPING ALKALOID SALT SOLUTIONS ON GUMS VIPONT LABORATORIES, INC. (US) 1987-07-28 US claimed
US-4599228-A Antimicrobial agent VIPONT LABORATORIES, INC. (US) 1986-07-08 US claimed
US-4590061-A BENZO-C-PHENANTHRIDINE ALKALOIDS VIPONT LABORATORIES, INC. (US) 1986-05-20 US claimed
EP-0149409-A2 Plate disclosing agent VIPONT PHARMACEUTICAL, INC. (US) 1985-07-24 EP claimed
US-4517172-A SANGUINARINE SALTS, ULTRAVILET LIGHT VIPONT LABORATORIES, INC. (US) 1985-05-14 US claimed
US-4406881-A ANTICARIES AGENTS, ALKALOIDS VIPONT LABORATORIES (US) 1983-09-27 US claimed