Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 5/20 | 0.54 |
| ▸ | CES2 | O00748 | 4/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | DAO | P14920 | 1/20 | 0.50 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA4 | P22748 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL367453 | 1.00 | CES1 (0.54) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL367456 | 1.00 | CES1 (0.54) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL11671741 | 0.84 | CES1 (0.61) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL11671738 | 0.84 | CES1 (0.61) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL5072437 | 0.82 | CES1 (0.52) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL6067697 | 0.82 | CES1 (0.52) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL1562541 | 0.82 | CES1 (0.52) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL1562534 | 0.82 | CES1 (0.52) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL10589355 | 0.82 | CES1 (0.52) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL585335 | 0.82 | CES1 (0.52) | CES1CES2TSHRALDH1A1DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1671698-A2 | Device for holding a substance library carrier | Clondiag Chip Technologies GmbH (DE) | 2006-06-21 | — | — | EP | claimed |
| EP-1436086-B1 | DEVICE FOR HOLDING A SUBSTANCE LIBRARY CARRIER | CLONDIAG CHIP TECH GMBH (DE) | 2006-03-29 | — | — | EP | claimed |
| EP-1633474-A1 | DEVICE FOR HOLDING AND DETECTING SUBSTANCE LIBRARIES | Clondiag Chip Technologies GmbH (DE) | 2006-03-15 | — | — | EP | claimed |
| US-20050047973-A1 | Device for holding a substance library carrier | CLONDIAG CHIP TECHNOLOGIES GMBH (DE) | 2005-03-03 | — | — | US | claimed |
| WO-2004103547-A1 | DEVICE FOR HOLDING AND DETECTING SUBSTANCE LIBRARIES | CLONDIAG CHIP TECHNOLOGIES GMBH (DE) | 2004-12-02 | — | — | WO | claimed |
| EP-1436086-A2 | DEVICE FOR HOLDING A SUBSTANCE LIBRARY CARRIER | Clondiag Chip Technologies GmbH (DE) | 2004-07-14 | — | — | EP | claimed |
| WO-2003031063-A2 | DEVICE FOR HOLDING A SUBSTANCE LIBRARY CARRIER | CLONDIAG CHIP TECHNOLOGIES GMBH (DE) | 2003-04-17 | — | — | WO | claimed |
| US-20170058334-A1 | REACTION VESSEL FOR CARRYING OUT ARRAY PROCESSES | CLONDIAG CHIP TECHNOLOGIES GMBH (DE) | 2017-03-02 | — | — | US | disclosed |
| EP-2305383-B1 | DEVICES FOR CARRYING OUT AND DIAGNOSING MICROARRAY EXPERIMENTS | CLONDIAG GMBH (DE) | 2016-04-27 | — | — | EP | disclosed |
| US-9310291-B2 | Reaction vessel for carrying out array processes | CLONDIAG CHIP TECHNOLOGIES GMBH (DE) | 2016-04-12 | — | — | US | disclosed |
| EP-2210665-B1 | Apparatus for detecting target molecules | CLONDIAG GMBH (DE) | 2014-07-09 | — | — | EP | disclosed |
| US-20110105572-A1 | CARBAMIC ACID COMPOUNDS COMPRISING AN AMIDE LINKAGE AS HDAC INHIBITORS | TOPOTARGET UK LIMITED (GB) | 2011-05-05 | — | — | US | disclosed |
| EP-2305383-A1 | Devices for carrying out and diagnosing microarray experiments | CLONDIAG GmbH (DE) | 2011-04-06 | — | — | EP | disclosed |
| US-20040092598-A1 | Carbamic acid compounds comprising an amide linkage as hdac inhibitors | TOPOTARGET UK LIMITED (GB) | 2004-05-13 | — | — | US | disclosed |
| EP-1335898-A1 | CARBAMIC ACID COMPOUNDS COMPRISING AN AMIDE LINKAGE AS HDAC INHIBITORS | Prolifix Limited (GB) | 2003-08-20 | — | — | EP | disclosed |
| WO-2003059516-A1 | REACTION VESSEL FOR CARRYING OUT ARRAY PROCESSES | CLONDIAG CHIP TECHNOLOGIES GMBH (DE) | 2003-07-24 | — | — | WO | disclosed |
| WO-2003031063-A2 | DEVICE FOR HOLDING A SUBSTANCE LIBRARY CARRIER | CLONDIAG CHIP TECHNOLOGIES GMBH (DE) | 2003-04-17 | — | — | WO | disclosed |
| WO-2002026696-A1 | CARBAMIC ACID COMPOUNDS COMPRISING AN AMIDE LINKAGE AS HDAC INHIBITORS | PROLIFIX LIMITED (GB) | 2002-04-04 | — | — | WO | disclosed |
| EP-0572900-A2 | Coating and its use in a process for preparing multilayer coatings | Herberts Gesellschaft mit beschränkter Haftung (DE) | 1993-12-08 | — | — | EP | disclosed |
| EP-0510762-A2 | Liquid cleaning products | UNILEVER N.V. (NL) | 1992-10-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040092598-A1 | Carbamic acid compounds comprising an amide linkage as hdac inhibitors | HDAC1, HDAC11, HDAC3 | CES1 157/4885CES2 875/4885TSHR 2954/4885 |
| US-20110105572-A1 | CARBAMIC ACID COMPOUNDS COMPRISING AN AMIDE LINKAGE AS HDAC INHIBITORS | HDAC1, HDAC7, HDAC5 | CES1 228/4885CES2 1249/4885TSHR 2210/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.