Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 5/20 | 0.52 |
| ▸ | CES2 | O00748 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | DAO | P14920 | 1/20 | 0.48 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1562534 | 1.00 | CES1 (0.52) | CES1CES2MAPTTSHRL3MBTL1 | |
| SCHEMBL1562541 | 1.00 | CES1 (0.52) | CES1CES2MAPTTSHRL3MBTL1 | |
| SCHEMBL26663883 | 0.85 | CES1 (0.58) | CES1CES2MAPTTSHRL3MBTL1 | |
| SCHEMBL367456 | 0.82 | CES1 (0.54) | CES1CES2MAPTTSHRL3MBTL1 | |
| SCHEMBL367453 | 0.82 | CES1 (0.54) | CES1CES2MAPTTSHRL3MBTL1 | |
| SCHEMBL1232452 | 0.82 | CES1 (0.54) | CES1CES2MAPTTSHRL3MBTL1 | |
| SCHEMBL631412 | 0.81 | TSHR (0.58) | CES1CES2MAPTTSHRL3MBTL1 | |
| SCHEMBL631411 | 0.81 | TSHR (0.58) | CES1CES2MAPTTSHRL3MBTL1 | |
| SCHEMBL585335 | 0.80 | CES1 (0.52) | CES1CES2MAPTTSHRL3MBTL1 | |
| SCHEMBL23198593 | 0.79 | CA12 (0.59) | MAPTCYP3A4HSD17B10PARP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1476181-A4 | POLYALKYLENE POLYMER COMPOUNDS AND USES THEREOF | BIOGEN IDEC INC (US) | 2008-11-19 | — | — | EP | disclosed |
| EP-1476181-A2 | POLYALKYLENE POLYMER COMPOUNDS AND USES THEREOF | Biogen Idec MA Inc. (US) | 2004-11-17 | — | — | EP | disclosed |
| WO-2003061577-A2 | POLYALKYLENE GLYCOL WITH MOIETY FOR CONJUGATING BIOLOGICALLY ACTIVE COMPOUND | BIOGEN IDEC MA INC. (US) | 2003-07-31 | — | — | WO | disclosed |