SCHEMBL123249

SCHEMBL123249

CCOC(=O)C(Br)CBr

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8616785 1.00
SCHEMBL240521 0.82 ZDHHC7 (0.47)
SCHEMBL1286734 0.82 ALDH1A1 (0.46)
SCHEMBL1732642 0.82
SCHEMBL1732696 0.82
SCHEMBL14016338 0.82 ALDH1A1 (0.46)
SCHEMBL36999 0.82 ZDHHC7 (0.47)
SCHEMBL189345 0.82
SCHEMBL698352 0.81 ALDH1A1 (0.44)
SCHEMBL11147083 0.81 ALDH1A1 (0.44)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 748 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115959993-B Synthesis method of 2-aryl propionic acid compound 山东中医药大学 2025-01-07 CN claimed
CN-117995558-A Preparation method of solid-state capacitance conductive polymer dispersion liquid 广东华鸿科技有限公司 2024-05-07 CN claimed
CN-117741025-A Method for detecting impurities in ethyl 2,3-dibromopropionate 石家庄四药有限公司 2024-03-22 CN claimed
CN-117209394-A Preparation method of diacetone acrylamide 潍坊科麦化工有限公司 2023-12-12 CN claimed
CN-115959993-A Synthetic method of 2-aryl propionic acid compound 山东中医药大学 2023-04-14 CN claimed
CN-110327842-A Octafluoropentanol-based fluorine-containing surfactant and preparation method thereof 四川轻化工大学 2019-10-15 CN claimed
CN-110041309-A A kind of Tacrine -8- amino (hydroxyl) quinoline of 2- carboxypiperazin connection and preparation and application 广东工业大学 2019-07-23 CN claimed
CN-104058991-B Novel Process For The Preparation Of Amino Acid Derivatives 优时比制药有限公司 2017-04-12 CN claimed
US-8946476-B2 Process for the preparation of amino acid derivatives UCB PHARMA GMBH (DE) 2015-02-03 US claimed
CN-104058991-A Novel Process For The Preparation Of Amino Acid Derivatives UCB PHARMA SA 2014-09-24 CN claimed
CN-102209707-B Novel process for producing amino acid derivative UCB PHARMA SA 2014-07-09 CN claimed
EP-2352721-B1 NOVEL PROCESS FOR THE PREPARATION OF AMINO ACID DERIVATIVES UCB PHARMA GMBH (DE) 2013-03-27 EP claimed
US-20110263899-A1 Novel Process for the Preparation of Amino Acid Derivatives UCB PHARMA GMBH (DE) 2011-10-27 US claimed
EP-2352721-A1 NOVEL PROCESS FOR THE PREPARATION OF AMINO ACID DERIVATIVES UCB Pharma GmbH (DE) 2011-08-10 EP claimed
WO-2010052011-A1 NOVEL PROCESS FOR THE PREPARATION OF AMINO ACID DERIVATIVES UCB PHARMA, S.A. (BE) 2010-05-14 WO claimed
EP-0894796-B1 Imidazolines substituted with a heterocyclic ring as alpha-2 antagonists ADIR (FR) 2001-06-06 EP claimed
EP-0669331-B1 Benzodioxane derivatives, process for their preparation and pharmaceutical compositions containing them ADIR (FR) 2000-10-11 EP claimed
US-6057321-A COMPOUNDS HAVING AFFINITY FOR 5-HYDROXYTRYPTAMINE SEROTONINERGIC RECEPTORS SANOFI-SYNTHELABO (FR) 2000-05-02 US claimed
JP-5255333-A None JP disclosed
US-4017512-A Process for producing N-alkylhydroxylamines SAGAMI CHEMICAL RESEARCH CENTER (JA) 1977-04-12 US disclosed