Sugi Predict

Sugi Predict / Compounds / SCHEMBL698352

SCHEMBL698352

SCHEMBL698352

CCOC(=O)C(Br)CCBr

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 3/20 0.44
▸ TRPA1 O75762 1/20 0.44
▸ ZDHHC7 Q9NXF8 1/20 0.42
▸ LMNA P02545 1/20 0.39
▸ HSD17B10 Q99714 1/20 0.39
▸ ALOX15 P16050 1/20 0.37
▸ MGAM O43451 1/20 0.37
▸ GAA P10253 1/20 0.37
▸ SI P14410 1/20 0.37
▸ MGAM2 Q2M2H8 1/20 0.37
▸ SOAT1 P35610 1/20 0.37
▸ L3MBTL1 Q9Y468 1/20 0.35
▸ CPB2 Q96IY4 1/20 0.34
▸ KMT2A Q03164 3/20 0.33
▸ CYP2D6 P10635 1/20 0.33
▸ CYP2C9 P11712 1/20 0.33
▸ CYP2C19 P33261 1/20 0.33
▸ POLB P06746 1/20 0.33
▸ LCK P06239 1/20 0.33
▸ PPARD Q03181 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL240521 0.88 ZDHHC7 (0.47) ALDH1A1TRPA1ZDHHC7LMNAHSD17B10
SCHEMBL36999 0.88 ZDHHC7 (0.47) ALDH1A1TRPA1ZDHHC7LMNAHSD17B10
SCHEMBL7036341 0.87 ZDHHC7 (0.48) ALDH1A1TRPA1ZDHHC7LMNAHSD17B10
SCHEMBL7971156 0.85 ZDHHC7 (0.52) ALDH1A1TRPA1ZDHHC7LMNAHSD17B10
SCHEMBL1415326 0.84 ZDHHC7 (0.59) ALDH1A1TRPA1ZDHHC7LMNAHSD17B10
SCHEMBL1415641 0.84 ZDHHC7 (0.53) ALDH1A1TRPA1ZDHHC7LMNAHSD17B10
SCHEMBL1021505 0.84 ZDHHC7 (0.53) ALDH1A1TRPA1ZDHHC7LMNAHSD17B10
SCHEMBL304907 0.84 ZDHHC7 (0.48) ALDH1A1TRPA1ZDHHC7LMNAHSD17B10
SCHEMBL1732719 0.84 ZDHHC7 (0.48) ALDH1A1TRPA1ZDHHC7LMNAHSD17B10
SCHEMBL1732564 0.84 ZDHHC7 (0.48) ALDH1A1TRPA1ZDHHC7LMNAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122094943-A Novel 1,2, 4-oxadiazoles as fungicides — 2026-05-26 — — CN disclosed
US-20250197378-A1 SMALL MOLECULE MODULATORS OF IL-17 LEO PHARMA AS (DK) 2025-06-19 — — US disclosed
WO-2025052333-A1 NOVEL 1,2,4-OXADIAZOLES COMPOUNDS AS FUNGICIDE PI INDUSTRIES LTD. (IN) 2025-03-13 — — WO disclosed
EP-4486737-A1 SMALL MOLECULE MODULATORS OF IL-17 LEO Pharma A/S (DK) 2025-01-08 — — EP disclosed
US-20240226113-A1 HETEROCYCLIC COMPOUNDS AND USES THEREOF KUMQUAT BIOSCIENCES INC. 2024-07-11 — — US disclosed
US-20240226113-A1 HETEROCYCLIC COMPOUNDS AND USES THEREOF KUMQUAT BIOSCIENCES INC. 2024-07-11 — — US disclosed
US-20230339970-A1 CASEIN KINASE 1 DELTA MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2023-10-26 — — US disclosed
US-20230339970-A1 CASEIN KINASE 1 DELTA MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2023-10-26 — — US disclosed
US-20230339970-A1 CASEIN KINASE 1 DELTA MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2023-10-26 — — US disclosed
WO-2023166172-A1 SMALL MOLECULE MODULATORS OF IL-17 LEO PHARMA A/S (DK) 2023-09-07 — — WO disclosed
US-20040157822-A1 Azetidinyl diamines useful as ligands of the nociceptin receptor ORL-1 BURNETT DUANE A (US) 2004-08-12 — — US disclosed
EP-1444200-A1 AZETIDINYL DIAMINES USEFUL AS LIGANDS OF THE NOCICEPTIN RECEPTOR ORL-1 SCHERING CORPORATION (US) 2004-08-11 — — EP disclosed
US-20030195185-A1 Azetidinyl diamines useful as ligands of the nociceptin receptor ORL-1 SCHERING CORPORATION 2003-10-16 — — US disclosed
EP-0827954-B1 Process for producing optically active azetidine-2-carboxylic acid SUMITOMO CHEMICAL CO (JP) 2003-06-04 — — EP disclosed
WO-2003043980-A1 AZETIDINYL DIAMINES USEFUL AS LIGANDS OF THE NOCICEPTIN RECEPTOR ORL-1 SCHERING CORPORATION (US) 2003-05-30 — — WO disclosed
US-6403534-B1 HERBICIDES; 1-(2-CHLORO-4-FLUORO-5-(3-METHYL-2,6-DIOXO-4-(TRIFLUOROMETHYL)-1,2,3,6 -TETRAHYDROPYRIMIDIN-1-YL) PHENOXY)CYCLOPROPANECARBOXYLATES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-06-11 — — US disclosed
US-6114543-A Process for producing optically active azetidine-2-carboxylic acid SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-09-05 — — US disclosed
US-5880291-A Process for producing optically active azetidine-2-carboxylic acid SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-03-09 — — US disclosed
EP-0827954-A1 Process for producing optically active azetidine-2-carboxylic acid SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1998-03-11 — — EP disclosed
US-4234744-A Process for the production of aminoacid hydrochlorides/or diaminoacid dihydrochlorides DEUTSCHE GOLD- UND SILBER SCHEIDEANSTALT VORMALS ROESSLER (DE) 1980-11-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250197378-A1 SMALL MOLECULE MODULATORS OF IL-17 IL17A, IL2, IL23R ALDH1A1 429/4885TRPA1 412/4885ZDHHC7 310/4885
US-20230339970-A1 CASEIN KINASE 1 DELTA MODULATORS CSNK1D, CSNK1A1, CSNK1G1 ALDH1A1 1482/4885TRPA1 3662/4885ZDHHC7 2710/4885
US-20240226113-A1 HETEROCYCLIC COMPOUNDS AND USES THEREOF TP53, HRAS, KRAS ALDH1A1 2917/4885TRPA1 3633/4885ZDHHC7 2228/4885
US-20030195185-A1 Azetidinyl diamines useful as ligands of the nociceptin receptor ORL-1 OPRL1, OPRD1, OPRM1 ALDH1A1 1235/4885TRPA1 74/4885ZDHHC7 928/4885
US-20040157822-A1 Azetidinyl diamines useful as ligands of the nociceptin receptor ORL-1 OPRL1, OPRD1, OPRM1 ALDH1A1 1235/4885TRPA1 74/4885ZDHHC7 928/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.