SCHEMBL12325307

SCHEMBL12325307

CCC(C)(CC)Oc1c(C)cc(-c2cc(C)c(OC(=O)c3cccc(C(=O)C(C)C)c3)c(C)c2)cc1C

nearest known ligand 0.36

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C19 P33261 1/20 0.33
PPARA Q07869 3/20 0.33
MAPT P10636 2/20 0.33
GAA P10253 2/20 0.33
F10 P00742 1/20 0.33
LMNA P02545 1/20 0.33
POLB P06746 1/20 0.33
TDP1 Q9NUW8 1/20 0.32
PPARG P37231 2/20 0.32
ADRB2 P07550 1/20 0.32
ADRB1 P08588 1/20 0.32
ADRB3 P13945 1/20 0.32
ESR1 P03372 1/20 0.32
ESR2 Q92731 1/20 0.32
KDM4E B2RXH2 1/20 0.31
DBH P09172 1/20 0.31
RECQL P46063 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13661724 0.86 CYP2D6 (0.46) CYP1A2CYP2D6CYP2C19PPARAMAPT
SCHEMBL13867764 0.84 PPARA (0.32) CYP1A2CYP2D6CYP2C19PPARAMAPT
SCHEMBL12325066 0.78 CYP1A2 (0.31) CYP1A2CYP2D6CYP2C19F10
SCHEMBL14211082 0.77 CYP2D6 (0.45) CYP1A2CYP2D6CYP2C19PPARAMAPT
SCHEMBL22446847 0.76 ALDH1A1 (0.38) CYP1A2CYP2D6CYP2C19PPARALMNA
SCHEMBL19805249 0.75 PPARA (0.34) CYP1A2CYP2D6CYP2C19PPARAPPARG
SCHEMBL23870271 0.75 HTT (0.39) CYP1A2PPARAMAPTGAALMNA
SCHEMBL16578017 0.74 CYP1A2 (0.40) CYP1A2CYP2D6CYP2C19PPARAESR1
SCHEMBL13359360 0.74 MAPT (0.40) CYP1A2CYP2D6CYP2C19PPARAMAPT
SCHEMBL13661695 0.72 MAPT (0.49) PPARAMAPTGAALMNATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011118845-A1 POLYESTER RESIN, AND OPTICAL MATERIALS, FILMS AND IMAGE DISPLAY DEVICES USING THE SAME FUJIFILM CORPORATION (JP) 2011-09-29 WO disclosed