SCHEMBL23870271

SCHEMBL23870271

CCC(C)(CC)Oc1c(C)cc(-c2cc(C)c(OC(C)=O)c(C)c2)cc1C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 3/20 0.39
KDM4E B2RXH2 2/20 0.39
HSD17B10 Q99714 2/20 0.39
TP53 P04637 1/20 0.39
GAA P10253 1/20 0.39
MAPT P10636 1/20 0.39
PPARA Q07869 5/20 0.35
ALDH1A1 P00352 1/20 0.34
HPGD P15428 1/20 0.34
POLB P06746 1/20 0.34
PPARG P37231 2/20 0.33
BACE1 P56817 1/20 0.33
LMNA P02545 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2C9 P11712 1/20 0.33
PPARD Q03181 1/20 0.33
PREP P48147 2/20 0.32
CELA1 Q9UNI1 1/20 0.32
ALOX5 P09917 2/20 0.31
PTPN1 P18031 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12352800 0.81 HTT (0.35) HTTKDM4EHSD17B10TP53GAA
SCHEMBL13661724 0.80 CYP2D6 (0.46) HSD17B10GAAMAPTPPARAALDH1A1
SCHEMBL19622461 0.77 HTT (0.42) HTTKDM4EHSD17B10TP53GAA
SCHEMBL18567239 0.76 HTT (0.40) HTTKDM4EHSD17B10TP53GAA
SCHEMBL12325307 0.75 CYP1A2 (0.33) KDM4EGAAMAPTPPARAPOLB
SCHEMBL12521523 0.74 CA1 (0.56) HTTKDM4EHSD17B10TP53GAA
SCHEMBL12445354 0.74 HTT (0.46) HTTKDM4EHSD17B10TP53GAA
SCHEMBL13762493 0.74 GLA (0.37) MAPTPPARA
SCHEMBL16578017 0.74 CYP1A2 (0.40) PPARAALDH1A1CYP1A2
SCHEMBL12950939 0.74 HTT (0.33) HTTKDM4EHSD17B10TP53GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210302849-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, ELECTROPHOTOGRAPHIC IMAGE FORMING APPARATUS, AND METHOD OF PRODUCING ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER CANON KABUSHIKI KAISHA (JP) 2021-09-30 US disclosed