SCHEMBL12326257

SCHEMBL12326257

CCCCCC(N)c1ccc(C(=O)OC)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 1/20 0.52
DPP4 P27487 2/20 0.52
ERAP2 Q6P179 2/20 0.48
LNPEP Q9UIQ6 2/20 0.48
MGLL Q99685 1/20 0.48
MAPT P10636 2/20 0.47
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
CASP1 P29466 1/20 0.47
LOXL2 Q9Y4K0 1/20 0.46
HPGD P15428 1/20 0.45
TLR8 Q9NR97 1/20 0.44
SLC6A2 P23975 1/20 0.44
SLC6A4 P31645 1/20 0.44
SLC6A3 Q01959 1/20 0.44
ALDH1A1 P00352 2/20 0.43
GRM2 Q14416 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP2C9 P11712 1/20 0.43
TSHR P16473 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14551497 1.00 SLC2A1 (0.52) SLC2A1DPP4ERAP2LNPEPMGLL
SCHEMBL20874440 0.96 DPP4 (0.49) SLC2A1DPP4ERAP2LNPEPMGLL
SCHEMBL10154458 0.95 DPP4 (0.53) SLC2A1DPP4ERAP2LNPEPMGLL
SCHEMBL12328884 0.95 DPP4 (0.53) SLC2A1DPP4ERAP2LNPEPMGLL
SCHEMBL14550338 0.89 DPP4 (0.56) DPP4ERAP2LNPEPMAPTNPC1
SCHEMBL12326223 0.89 DPP4 (0.56) DPP4ERAP2LNPEPMAPTNPC1
SCHEMBL14551612 0.85 SLC2A1 (0.50) SLC2A1DPP4MAPTNPC1RAB9A
SCHEMBL14551926 0.85 SLC2A1 (0.50) SLC2A1DPP4MAPTNPC1RAB9A
SCHEMBL28291146 0.84 MGLL (0.50) ERAP2LNPEPMGLLMAPTNPC1
SCHEMBL1765677 0.84 MGLL (0.50) MGLLMAPTNPC1RAB9ACASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109415553-A The thermosetting resin of plasticising and related solidified resin, curing method and the product comprising solidified resin 马萨诸塞大学 2019-03-01 CN claimed
EP-3481899-B1 PLASTICIZED THERMOSET RESIN, AND ASSOCIATED CURED RESIN, METHOD OF CURING, AND ARTICLE COMPRISING CURED RESIN UNIV MASSACHUSETTS (US) 2022-12-21 EP disclosed
US-10913844-B2 Plasticized thermoset resin, and associated cured resin, method of curing, and article comprising cured resin THE UNIVERSITY OF MASSACHUSETTS (US) 2021-02-09 US disclosed
US-20190309159-A1 PLASTICIZED THERMOSET RESIN, AND ASSOCIATED CURED RESIN, METHOD OF CURING, AND ARTICLE COMPRISING CURED RESIN THE UNIVERSITY OF MASSACHUSETTS 2019-10-10 US disclosed
CN-109415553-A The thermosetting resin of plasticising and related solidified resin, curing method and the product comprising solidified resin 马萨诸塞大学 2019-03-01 CN disclosed
WO-2011119559-A1 NOVEL SPIRO IMIDAZOLONES AS GLUCAGON RECEPTOR ANTAGONISTS, COMPOSITIONS, AND METHODS FOR THEIR USE SCHERING CORPORATION (US) 2011-09-29 WO disclosed
WO-2010039789-A1 SPIRO-IMIDAZOLONE DERIVATIVES AS GLUCAGON RECEPTOR ANTAGONISTS SCHERING CORPORATION (US) 2010-04-08 WO disclosed