Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.57 |
| ▸ | F2 | P00734 | 1/20 | 0.54 |
| ▸ | PLG | P00747 | 1/20 | 0.54 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.54 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.54 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19070659 | 0.83 | F2 (0.56) | PBRM1F2PLGPRSS1PRSS2 | |
| SCHEMBL16396188 | 0.82 | PBRM1 (0.59) | PBRM1F2PLGPRSS1PRSS2 | |
| SCHEMBL14142782 | 0.81 | F2 (0.59) | PBRM1F2PLGPRSS1PRSS2 | |
| SCHEMBL771139 | 0.79 | F2 (0.52) | PBRM1F2PLGPRSS1PRSS2 | |
| SCHEMBL7066984 | 0.79 | PBRM1 (0.60) | PBRM1F2PLGPRSS1PRSS2 | |
| SCHEMBL3147361 | 0.77 | F2 (0.50) | PBRM1F2PLGPRSS1PRSS2 | |
| 3-Aminobenzoic Acid SCHEMBL27259078 | 0.77 | PBRM1 (0.64) | PBRM1F2PLGPRSS1PRSS2 | |
| SCHEMBL23480192 | 0.76 | PBRM1 (0.69) | PBRM1F2PLGPRSS1PRSS2 | |
| 3-Aminobenzoic Acid SCHEMBL27648 | 0.76 | PBRM1 (0.69) | PBRM1F2PLGPRSS1PRSS2 | |
| 3-Aminobenzoic Acid SCHEMBL8003706 | 0.76 | PBRM1 (0.69) | PBRM1F2PLGPRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9477148-B1 | Polymer, method for preparing the same, and a photosensitive resin composition thereof | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2016-10-25 | — | — | US | disclosed |
| US-9216966-B2 | Compounds for Alzheimer's disease | Manfredi, John (US) | 2015-12-22 | — | — | US | disclosed |
| US-8389767-B2 | Processes and compounds | SYNGENTA CROP PROTECTION LLC (US) | 2013-03-05 | — | — | US | disclosed |
| US-20120309812-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2012-12-06 | — | — | US | disclosed |
| EP-2366699-A1 | 8-SUBSTITUTED ISOQUINOLINE DERIVATIVE AND USE THEREOF | Asahi Kasei Pharma Corporation (JP) | 2011-09-21 | — | — | EP | disclosed |
| US-20100240712-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-09-23 | — | — | US | disclosed |
| US-20100204504-A1 | NOVEL PROCESSES AND COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120309812-A1 | INSECTICIDAL COMPOUNDS | ACHE, AADAC, NISCH | PBRM1 3862/4885F2 2179/4885PLG 3093/4885 |
| US-20100204504-A1 | NOVEL PROCESSES AND COMPOUNDS | DDT, CYP4B1, CYP4F3 | PBRM1 3344/4885F2 197/4885PLG 2252/4885 |
| US-20100240712-A1 | INSECTICIDAL COMPOUNDS | CHRM1, CHRM2, ACHE | PBRM1 4781/4885F2 315/4885PLG 4773/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.