Actinonin

Actinonin

SCHEMBL123273

CCCCCC(CC(=O)NO)C(=O)NC(C(=O)N1CCCC1CO)C(C)C

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
BIRC2 Q13490 5/20 0.56
MMP3 P08254 12/20 0.46
MMP1 P03956 9/20 0.46
MMP2 P08253 8/20 0.46
MMP7 P09237 3/20 0.46
MMP9 P14780 3/20 0.46
MMP14 P50281 1/20 0.42
PDF Q9HBH1 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Actinonin SCHEMBL279450 1.00 BIRC2 (0.56) BIRC2MMP3MMP1MMP2MMP7
Actinonin SCHEMBL279122 1.00 BIRC2 (0.56) BIRC2MMP3MMP1MMP2MMP7
Actinonin SCHEMBL14490676 1.00 BIRC2 (0.56) BIRC2MMP3MMP1MMP2MMP7
Actinonin SCHEMBL12601775 1.00 BIRC2 (0.56) BIRC2MMP3MMP1MMP2MMP7
SCHEMBL6294118 0.97 BIRC2 (0.55) BIRC2MMP3MMP1MMP2MMP7
SCHEMBL18328823 0.92 MMP3 (0.49) BIRC2MMP3MMP1MMP2MMP7
SCHEMBL21387112 0.92 BIRC2 (0.47) BIRC2MMP3MMP1MMP2MMP7
SCHEMBL14279424 0.90 BIRC2 (0.55) BIRC2MMP3MMP1MMP2MMP7
SCHEMBL6294172 0.87 BIRC2 (0.58) BIRC2MMP3MMP1MMP2MMP7
SCHEMBL9495973 0.87 BIRC2 (0.44) BIRC2MMP3MMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2273 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025151884-A1 USE OF GLYCOSAMINOGLYCAN SULFATED POLYSACCHARIDES SUCH AS SODIUM PENTOSAN POLYSULFATE IN COMBINATION WITH PERMEATION AGENTS TO TREAT ALZHEIMER'S DISEASE PARSONS C LOWELL (US) 2025-07-17 WO claimed
WO-2025073942-A1 MUSCLE STEM CELL CULTURE UNIVERSITY OF HELSINKI (FI) 2025-04-10 WO claimed
CN-119698270-A Composition and method for producing the same 阿马曾提斯公司 2025-03-25 CN claimed
EP-4496562-A1 COMPOSITIONS Amazentis SA (CH) 2025-01-29 EP claimed
US-20240342175-A1 Compositions and Methods for Treating Spinal Cord Injury and Synaptic Dysfunction MITZ HOWARD (US) 2024-10-17 US claimed
CN-118464557-A Preparation method and evaluation method of docetaxel NLC delivery system 吉林医药学院 2024-08-09 CN claimed
US-20240189317-A1 ANTIVIRAL COMPOSITIONS AND METHODS ACADIA WOODS PARTNERS, LLC 2024-06-13 US claimed
EP-4319877-A1 COMPOSITIONS AND METHODS FOR TREATING SPINAL CORD INJURY AND SYNAPTIC DYSFUNCTION Mitz, Howard (US) 2024-02-14 EP claimed
EP-4308103-A1 ANTIVIRAL COMPOSITIONS AND METHODS AI Therapeutics, Inc. (US) 2024-01-24 EP claimed
US-20230413828-A1 BIOHERBICIDES FOR CONTROLLING ONE OR MORE PLANT SPECIES AGROSPHERES, INC. 2023-12-28 US claimed
EP-0424193-B1 Use of actinonin for the manufacture of a medicament for angiogenesis inhibition ZAIDAN HOJIN BISEIBUTSU (JP) 1994-01-12 EP claimed
EP-0296040-B1 ACTINONIN DERIVATIVES HAVING PHYSIOLOGICAL ACTIVITIES ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) 1993-04-28 EP claimed
US-5206384-A Enzyme inhibitors ZAIDAN HOJIN BISEIBUTSU KAGAKU KAI (JP) 1993-04-27 US claimed
US-5134156-A Antiinflammatory agents or antidiabetic agents ZAIDAN HOJIN BISEIBUTSU KAGAKU KAI (JP) 1992-07-28 US claimed
EP-0474553-A1 Actinonin derivatives ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) 1992-03-11 EP claimed
EP-0424193-A2 Use of actinonin for the manufacture of a medicament for angiogenesis inhibition ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) 1991-04-24 EP claimed
US-4929633-A ENZYME INHIBITORS, PEPTIDASES, ANTIAMNESIA AGENTS ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) 1990-05-29 US claimed
EP-0296040-A1 Actinonin derivatives having physiological activities ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) 1988-12-21 EP claimed
US-4663342-A ANTITUMOR ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) 1987-05-05 US claimed
EP-0167936-A2 Use of actinonin as an immunopotentiator MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) 1986-01-15 EP claimed