Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BIRC2 | Q13490 | 4/20 | 0.47 |
| ▸ | MMP3 | P08254 | 11/20 | 0.38 |
| ▸ | MMP1 | P03956 | 9/20 | 0.38 |
| ▸ | MMP2 | P08253 | 8/20 | 0.38 |
| ▸ | MMP7 | P09237 | 3/20 | 0.38 |
| ▸ | MMP9 | P14780 | 3/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
| ▸ | MMP14 | P50281 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | Q9HBH1 | 1/20 | 0.34 | |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Actinonin SCHEMBL279122 | 0.92 | BIRC2 (0.56) | BIRC2MMP3MMP1MMP2MMP7 | |
| Actinonin SCHEMBL14490676 | 0.92 | BIRC2 (0.56) | BIRC2MMP3MMP1MMP2MMP7 | |
| Actinonin SCHEMBL123273 | 0.92 | BIRC2 (0.56) | BIRC2MMP3MMP1MMP2MMP7 | |
| Actinonin SCHEMBL12601775 | 0.92 | BIRC2 (0.56) | BIRC2MMP3MMP1MMP2MMP7 | |
| Actinonin SCHEMBL279450 | 0.92 | BIRC2 (0.56) | BIRC2MMP3MMP1MMP2MMP7 | |
| SCHEMBL21387785 | 0.92 | BIRC2 (0.46) | BIRC2MMP3MMP1MMP2MMP7 | |
| SCHEMBL6294118 | 0.90 | BIRC2 (0.55) | BIRC2MMP3MMP1MMP2MMP7 | |
| SCHEMBL9495973 | 0.85 | BIRC2 (0.44) | BIRC2MMP3MMP1DPP4DPP8 | |
| SCHEMBL18328823 | 0.85 | MMP3 (0.49) | BIRC2MMP3MMP1MMP2MMP7 | |
| SCHEMBL21481097 | 0.84 | BIRC2 (0.39) | BIRC2MMP3MMP1MMP9DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3543349-A1 | MOLECULAR KINETICS EVALUATION METHOD AND SCREENING METHOD | Tokyo University of Science Foundation (JP) | 2019-09-25 | — | — | EP | disclosed |
| EP-3542824-A1 | Ras PROTEIN DEGRADATION INDUCING MOLECULE AND PHARMACEUTICAL COMPOSITION | Tokyo University of Science Foundation (JP) | 2019-09-25 | — | — | EP | disclosed |