Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.47 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | STAT1 | P42224 | 1/20 | 0.43 |
| ▸ | TOP1 | P11387 | 3/20 | 0.43 |
| ▸ | CYCS | P99999 | 4/20 | 0.42 |
| ▸ | RHEB | Q15382 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14708796 | 0.90 | ABCG2 (0.56) | ABCG2STAT3STAT1TOP1CYCS | |
| SCHEMBL13547831 | 0.87 | STAT3 (0.56) | ABCG2STAT3STAT1TOP1CYCS | |
| SCHEMBL14706937 | 0.86 | ABCG2 (0.55) | ABCG2STAT3STAT1TOP1CYCS | |
| SCHEMBL7261867 | 0.82 | STAT3 (0.51) | ABCG2STAT3STAT1TOP1CYCS | |
| SCHEMBL14706938 | 0.80 | ABCG2 (0.53) | ABCG2STAT3STAT1TOP1CYCS | |
| SCHEMBL13411108 | 0.80 | ABCG2 (0.49) | ABCG2STAT3STAT1TOP1CYCS | |
| SCHEMBL3892703 | 0.78 | ABCG2 (0.71) | ABCG2TOP1CYCSRHEBSMN1; SMN2 | |
| SCHEMBL29583274 | 0.78 | ABCG2 (0.71) | ABCG2TOP1CYCSRHEBSMN1; SMN2 | |
| SCHEMBL14706940 | 0.77 | ABCG2 (0.51) | ABCG2STAT3STAT1TOP1CYCS | |
| SCHEMBL28491269 | 0.77 | ABCG2 (0.70) | ABCG2TOP1CYCSRHEBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011111725-A1 | NOVEL PORPHYRIN COMPLEX AND USE THEREOF | 国立大学法人京都大学 (JP) | 2011-09-15 | — | — | WO | disclosed |