SCHEMBL3892703

SCHEMBL3892703

COC(=O)c1ccc(-c2c3nc(c(-c4ccc(C(=O)OC)cc4)c4ccc([nH]4)c(-c4ccc(C(=O)OC)cc4)c4nc(c(-c5ccc(C(=O)OC)cc5)c5ccc2[nH]5)C=C4)C=C3)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ABCG2 Q9UNQ0 1/20 0.71
▸ TOP1 P11387 4/20 0.68
▸ CYCS P99999 4/20 0.67
▸ ENPP2 Q13822 1/20 0.54
▸ TERT O14746 4/20 0.50
▸ KDM4E B2RXH2 2/20 0.50
▸ ALDH1A1 P00352 2/20 0.50
▸ NPC1 O15118 1/20 0.50
▸ LMNA P02545 1/20 0.50
▸ PKM P14618 1/20 0.50
▸ HPGD P15428 1/20 0.50
▸ NFKB1 P19838 1/20 0.50
▸ RAB9A P51151 1/20 0.50
▸ NFKB2 Q00653 1/20 0.50
▸ RELA Q04206 1/20 0.50
▸ SMN1; SMN2 Q16637 1/20 0.50
▸ RHEB Q15382 1/20 0.47
▸ MMP2 P08253 1/20 0.46
▸ MMP9 P14780 1/20 0.46
▸ MMP8 P22894 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29583274 1.00 ABCG2 (0.71) ABCG2TOP1CYCSENPP2TERT
SCHEMBL28463987 0.99 ABCG2 (0.70) ABCG2TOP1CYCSENPP2TERT
SCHEMBL30872331 0.99 ABCG2 (0.70) ABCG2TOP1CYCSENPP2TERT
SCHEMBL28491269 0.99 ABCG2 (0.70) ABCG2TOP1CYCSENPP2TERT
SCHEMBL28498163 0.99 ABCG2 (0.70) ABCG2TOP1CYCSENPP2TERT
SCHEMBL28131499 0.99 ABCG2 (0.70) ABCG2TOP1CYCSENPP2TERT
Hydrochloric Acid SCHEMBL28130818 0.97 ABCG2 (0.68) ABCG2TOP1CYCSENPP2TERT
SCHEMBL28130817 0.96 ABCG2 (0.67) ABCG2TOP1CYCSENPP2TERT
SCHEMBL25046485 0.95 TOP1 (0.66) ABCG2TOP1CYCSENPP2TERT
SCHEMBL30925006 0.95 TOP1 (0.66) ABCG2TOP1CYCSENPP2TERT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12565426-B2 Photothermal catalytic method for production of hydrogen peroxide without sacrificial reagents on basis of porphyrin-based supermolecule JIANGNAN UNIVERSITY (CN) 2026-03-03 — — US claimed
US-20220340423-A1 Photothermal Catalytic Method for Production of Hydrogen Peroxide without Sacrificial Reagents on Basis of Porphyrin-based Supermolecule JIANGNAN UNIVERSITY (CN) 2022-10-27 — — US claimed
US-20180259693-A1 PHOTO-STABLE AND THERMALLY-STABLE DYE COMPOUNDS FOR SELECTIVE BLUE LIGHT FILTERED OPTIC FRONTIER SCIENTIFIC, INC. (US) 2018-09-13 — — US claimed
US-20170235034-A1 PHOTO-STABLE AND THERMALLY-STABLE DYE COMPOUNDS FOR SELECTIVE BLUE LIGHT FILTERED OPTIC FRONTIER SCIENTIFIC, INC. (US) 2017-08-17 — — US claimed
CN-106432366-A Preparation and application of nano metal-organic framework material PCN-223 based on porphyrin ligand 哈尔滨理工大学 2017-02-22 — — CN claimed
EP-1353925-A2 PROCESSES FOR LARGE SCALE PRODUCTION OF TETRAPYRROLES Miravant Pharmaceuticals, Inc. (US) 2003-10-22 — — EP claimed
WO-2002083686-A2 PROCESSES FOR LARGE SCALE PRODUCTION OF TETRAPYRROLES MIRAVANT PHARMACEUTICALS, INC. (US) 2002-10-24 — — WO claimed
US-6462192-B2 SUCH AS MESO-FORMYL PORPHYRINS, MESO-ACRYLATE PORPHYRINS, PURPURINS AND BENZOCHLORINS. IN PARTICULAR, TIN ETHYL ETIOPURPURIN (SNET2) AND THE INTERMEDIATES NECESSARY FOR ITS PRODUCTION WITHOUT CHROMATOGRAPHY MIRAVANT PHARMACEUTICALS, INC. 2002-10-08 — — US claimed
US-20020137924-A1 Processes for large scale production of tetrapyrroles MIRAVANT PHARMACEUTICALS, INC. 2002-09-26 — — US claimed
US-12565426-B2 Photothermal catalytic method for production of hydrogen peroxide without sacrificial reagents on basis of porphyrin-based supermolecule JIANGNAN UNIVERSITY (CN) 2026-03-03 — — US disclosed
US-20230302144-A1 Porphyrin Compounds and Compositions Useful for Treating Cancer ONCOSELECT THERAPEUTICS, LLC (US) 2023-09-28 — — US disclosed
US-11590233-B2 Porphyrin compounds and compositions useful for treating cancer ONCOSELECT THERAPEUTICS, LLC (US) 2023-02-28 — — US disclosed
US-20230051807-A1 PORPHYRIN PHOTOSENSITIZER AND COBALOXIME COCATALYST AND METHODS OF USE THEREOF THE HONG KONG POLYTECHNIC UNIVERSITY (CN) 2023-02-16 — — US disclosed
US-20220340423-A1 Photothermal Catalytic Method for Production of Hydrogen Peroxide without Sacrificial Reagents on Basis of Porphyrin-based Supermolecule JIANGNAN UNIVERSITY (CN) 2022-10-27 — — US disclosed
WO-2007047582-A2 PORPHYRIN COMPOUNDS FOR ENHANCING MITOCHONDRIAL FUNCTION THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2007-04-26 — — WO disclosed
US-20040076585-A1 Nanoparticles of cyclic tetrapyrrolic compounds as gene and drug delivery carriers GONG XIANCHANG (US) 2004-04-22 — — US disclosed
EP-1353925-A2 PROCESSES FOR LARGE SCALE PRODUCTION OF TETRAPYRROLES Miravant Pharmaceuticals, Inc. (US) 2003-10-22 — — EP disclosed
WO-2002083686-A2 PROCESSES FOR LARGE SCALE PRODUCTION OF TETRAPYRROLES MIRAVANT PHARMACEUTICALS, INC. (US) 2002-10-24 — — WO disclosed
US-6462192-B2 SUCH AS MESO-FORMYL PORPHYRINS, MESO-ACRYLATE PORPHYRINS, PURPURINS AND BENZOCHLORINS. IN PARTICULAR, TIN ETHYL ETIOPURPURIN (SNET2) AND THE INTERMEDIATES NECESSARY FOR ITS PRODUCTION WITHOUT CHROMATOGRAPHY MIRAVANT PHARMACEUTICALS, INC. 2002-10-08 — — US disclosed
US-20020137924-A1 Processes for large scale production of tetrapyrroles MIRAVANT PHARMACEUTICALS, INC. 2002-09-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230051807-A1 PORPHYRIN PHOTOSENSITIZER AND COBALOXIME COCATALYST AND METHODS OF USE THEREOF PPOX, HMBS, PNPO ABCG2 1887/4885TOP1 2957/4885CYCS 297/4885
US-12565426-B2 Photothermal catalytic method for production of hydrogen peroxide without sacrificial reagents on basis of porphyrin-based supermolecule TPO, PPOX, THPO ABCG2 2368/4885TOP1 446/4885CYCS 282/4885
US-20230302144-A1 Porphyrin Compounds and Compositions Useful for Treating Cancer KIT, HCCS, PPIF ABCG2 559/4885TOP1 176/4885CYCS 256/4885
US-11590233-B2 Porphyrin compounds and compositions useful for treating cancer KIT, HCCS, PPIF ABCG2 559/4885TOP1 176/4885CYCS 256/4885
US-20020137924-A1 Processes for large scale production of tetrapyrroles SNU13, NPEPPS, ESYT2 ABCG2 1070/4885TOP1 2944/4885CYCS 3508/4885
US-20040076585-A1 Nanoparticles of cyclic tetrapyrrolic compounds as gene and drug delivery carriers CCDC6, CCDC47, ABCB1 ABCG2 1644/4885TOP1 298/4885CYCS 1404/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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