Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.55 |
| ▸ | TOP1 | P11387 | 3/20 | 0.48 |
| ▸ | STAT3 | P40763 | 1/20 | 0.48 |
| ▸ | STAT1 | P42224 | 1/20 | 0.48 |
| ▸ | CYCS | P99999 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | RHEB | Q15382 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.41 |
| ▸ | RELA | Q04206 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14708796 | 0.96 | ABCG2 (0.56) | ABCG2TOP1STAT3STAT1CYCS | |
| SCHEMBL13547831 | 0.92 | STAT3 (0.56) | ABCG2TOP1STAT3STAT1CYCS | |
| SCHEMBL14706938 | 0.89 | ABCG2 (0.53) | ABCG2TOP1STAT3STAT1CYCS | |
| SCHEMBL13411108 | 0.89 | ABCG2 (0.49) | ABCG2TOP1STAT3STAT1CYCS | |
| SCHEMBL7261867 | 0.87 | STAT3 (0.51) | ABCG2TOP1STAT3STAT1CYCS | |
| SCHEMBL12328375 | 0.86 | ABCG2 (0.47) | ABCG2TOP1STAT3STAT1CYCS | |
| SCHEMBL14706940 | 0.86 | ABCG2 (0.51) | ABCG2TOP1STAT3STAT1CYCS | |
| SCHEMBL5319095 | 0.83 | STAT3 (0.64) | ABCG2TOP1STAT3STAT1CYCS | |
| SCHEMBL30205816 | 0.83 | STAT3 (0.64) | ABCG2TOP1STAT3STAT1CYCS | |
| SCHEMBL30519987 | 0.83 | STAT3 (0.64) | ABCG2TOP1STAT3STAT1CYCS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8846905-B2 | Porphyrin complex and use thereof | KYOTO UNIVERSITY (JP) | 2014-09-30 | — | — | US | disclosed |
| US-20130042916-A1 | NOVEL PORPHYRIN COMPLEX AND USE THEREOF | KYOTO UNIVERSITY (JP) | 2013-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130042916-A1 | NOVEL PORPHYRIN COMPLEX AND USE THEREOF | PPOX, TYR, DDT | ABCG2 2416/4885TOP1 2433/4885STAT3 3595/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.