⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8057836 | 0.74 | ALDH1A1 (0.36) | — | |
| SCHEMBL907971 | 0.74 | — | — | |
| SCHEMBL8673228 | 0.74 | — | — | |
| SCHEMBL10762130 | 0.73 | — | — | |
| SCHEMBL436900 | 0.73 | — | — | |
| SCHEMBL25243423 | 0.73 | — | — | |
| SCHEMBL195701 | 0.71 | — | — | |
| SCHEMBL8469447 | 0.69 | — | — | |
| SCHEMBL5422567 | 0.69 | — | — | |
| SCHEMBL2769212 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102286026-A | Acyclic nucleotide analogue, crystal form and medicinal composition thereof | — | 2011-12-21 | — | — | CN | claimed |
| CN-1266156-C | Synthesis process for Adefovir ester of anti hepatitis type B virus medicine | HU XIAOXIA (CN) | 2006-07-26 | — | — | CN | claimed |
| CN-1560059-A | Synthesis process for Adefovir ester of anti hepatitis type B virus medicine | 胡小侠 | 2005-01-05 | — | — | CN | claimed |
| EP-4511035-A1 | CTPS1 INHIBITORS AND USES THEREOF | Nimbus Clotho, Inc. (US) | 2025-02-26 | — | — | EP | disclosed |
| WO-2023205475-A1 | CTPS1 INHIBITORS AND USES THEREOF | NIMBUS CLOTHO, INC. (US) | 2023-10-26 | — | — | WO | disclosed |
| EP-4081521-A1 | SUBSTITUTED TRICYCLIC COMPOUNDS | Lupin Limited (IN) | 2022-11-02 | — | — | EP | disclosed |
| WO-2021130731-A1 | SUBSTITUTED TRICYCLIC COMPOUNDS | LUPIN LIMITED (IN) | 2021-07-01 | — | — | WO | disclosed |
| CN-109006823-B | Application of 2-aryl substituted pyrrole compound in oncomelania killing drug | 江苏省血吸虫病防治研究所 | 2021-05-07 | — | — | CN | disclosed |
| CN-109169668-B | Application of 2-aryl substituted pyrrole compound in drug for killing vesicular snails | 江苏省血吸虫病防治研究所 | 2021-05-07 | — | — | CN | disclosed |
| CN-109006824-B | Application of 2-aryl substituted pyrrole compound in medicament for killing amphioxus | 江苏省血吸虫病防治研究所 | 2021-04-27 | — | — | CN | disclosed |
| EP-3426243-A1 | 3-PHOSPHOGLYCERATE DEHYDROGENASE INHIBITORS AND USES THEREOF | Raze Therapeutics Inc. (US) | 2019-01-16 | — | — | EP | disclosed |
| EP-1486480-A1 | Adamantyl vinyl ether compound and production process for the same | Idemitsu Petrochemical Co., Ltd. (JP) | 2004-12-15 | — | — | EP | disclosed |
| US-6825348-B2 | Antiviral compounds | ACADEMIA SINICA (TW) | 2004-11-30 | — | — | US | disclosed |
| WO-2004056745-A2 | ADAMANTYL ACETAMIDES AS 11-BETA HYDROXYSTEROID DEHYDROGENASE INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2004-07-08 | — | — | WO | disclosed |
| US-20040002475-A1 | Dna genome | ACADEMIA SINICA (TW) | 2004-01-01 | — | — | US | disclosed |
| EP-0533833-B1 | PHOSPHOROUS PRODUGS | GLAZIER ARNOLD (US) | 1995-12-20 | — | — | EP | disclosed |
| EP-0533833-A1 | PHOSPHOROUS PRODRUGS. | GLAZIER ARNOLD (US) | 1993-03-31 | — | — | EP | disclosed |
| WO-1991019721-A1 | PHOSPHOROUS PRODUGS | GLAZIER ARNOLD (US) | 1991-12-26 | — | — | WO | disclosed |
| EP-0033255-B1 | OXIMES DERIVED FROM ERYTHROMYCIN A, THEIR PREPARATION, THEIR APPLICATION IN PHARMACEUTICALS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ROUSSEL-UCLAF (FR) | 1984-08-29 | — | — | EP | disclosed |
| EP-0033255-A1 | Oximes derived from erythromycin A, their preparation, their application in pharmaceuticals and pharmaceutical compositions containing them | ROUSSEL-UCLAF (FR) | 1981-08-05 | — | — | EP | disclosed |