SCHEMBL12331002

SCHEMBL12331002

NC(=O)N1CCOC(I)C1

nearest known ligand 0.35

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PDK1 Q15118 5/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6868433 0.80 SMN1; SMN2 (0.47) PDK1
SCHEMBL12331039 0.78 HPGD (0.45)
SCHEMBL31622185 0.76 PDK1 (0.46) PDK1
SCHEMBL675833 0.76 PDK1 (0.55) PDK1
SCHEMBL12331051 0.76 TSHR (0.47)
SCHEMBL12331619 0.76 CHRNB2 (0.42) PDK1
SCHEMBL12331070 0.76 TSHR (0.35) PDK1
SCHEMBL14773659 0.76 CHRNB2 (0.42) PDK1
SCHEMBL12331052 0.76 PDK1 (0.33) PDK1
SCHEMBL12331003 0.76 POLB (0.47) PDK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013036684-A1 COMPOUNDS USEFUL FOR TREATING NEURODEGENERATIVE DISORDERS SATORI PHARMACEUTICALS, INC (US) 2013-03-14 WO disclosed
WO-2011109657-A1 COMPOUNDS USEFUL FOR TREATING NEURODEGENERATIVE DISORDERS SATORI PHARMACEUTICALS, INC. (US) 2011-09-09 WO disclosed