Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.37 |
| ▸ | ACLY | P53396 | 2/20 | 0.37 |
| ▸ | ACACA | Q13085 | 2/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 7/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 6/20 | 0.31 |
| ▸ | PSEN2 | P49810 | 6/20 | 0.31 |
| ▸ | APH1B | Q8WW43 | 6/20 | 0.31 |
| ▸ | NCSTN | Q92542 | 6/20 | 0.31 |
| ▸ | APH1A | Q96BI3 | 6/20 | 0.31 |
| ▸ | PSENEN | Q9NZ42 | 6/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12332241 | 0.77 | PSEN1 (0.49) | HSD11B1HSD11B2ACLYACACAPTPN11 | |
| SCHEMBL12331892 | 0.75 | PSEN1 (0.49) | HSD11B1HSD11B2ACLYACACAPTPN11 | |
| SCHEMBL12331275 | 0.74 | PSEN1 (0.51) | HSD11B1HSD11B2ACLYACACAAPP | |
| SCHEMBL14773157 | 0.73 | ACLY (0.33) | HSD11B1HSD11B2ACLYACACA | |
| SCHEMBL14768574 | 0.73 | ACLY (0.33) | HSD11B1HSD11B2ACLYACACA | |
| SCHEMBL14768521 | 0.72 | APP (0.53) | APPCYP3A4 | |
| SCHEMBL14773587 | 0.72 | PSEN1 (0.40) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL14772438 | 0.71 | PSEN1 (0.42) | HSD11B1HSD11B2ACLYACACAAPP | |
| SCHEMBL14753006 | 0.71 | PTPN11 (0.48) | HSD11B1HSD11B2ACLYACACAPTPN11 | |
| SCHEMBL14773069 | 0.69 | APP (0.57) | APPCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011109657-A1 | COMPOUNDS USEFUL FOR TREATING NEURODEGENERATIVE DISORDERS | SATORI PHARMACEUTICALS, INC. (US) | 2011-09-09 | — | — | WO | disclosed |