Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 2/20 | 0.33 |
| ▸ | ACACA | Q13085 | 2/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.32 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14768574 | 1.00 | ACLY (0.33) | ACLYACACAHSD11B1HSD11B2 | |
| SCHEMBL14753721 | 0.80 | PSEN1 (0.36) | — | |
| SCHEMBL14768899 | 0.79 | PSEN1 (0.33) | — | |
| SCHEMBL12331095 | 0.73 | HSD11B1 (0.37) | ACLYACACAHSD11B1HSD11B2 | |
| SCHEMBL14773138 | 0.71 | PSEN1 (0.42) | — | |
| SCHEMBL14773195 | 0.71 | PSEN1 (0.42) | — | |
| SCHEMBL14773582 | 0.67 | PSEN1 (0.41) | — | |
| SCHEMBL12331078 | 0.67 | PSEN1 (0.46) | — | |
| SCHEMBL14773587 | 0.65 | PSEN1 (0.40) | — | |
| SCHEMBL14753715 | 0.65 | PSEN1 (0.67) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013036665-A1 | COMPOUNDS FOR USE IN TREATING NEURODEGENERATIVE DISORDERS, SYNTHESIS THEREOF, AND INTERMEDIATES THERETO | SATORI PHARMACEUTICALS, INC. (US) | 2013-03-14 | — | — | WO | disclosed |