⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12330856 | 1.00 | — | — | |
| SCHEMBL12124909 | 1.00 | — | — | |
| SCHEMBL8991462 | 0.87 | LMNA (0.53) | — | |
| SCHEMBL901987 | 0.79 | LMNA (0.45) | — | |
| SCHEMBL19963491 | 0.78 | LMNA (0.35) | — | |
| SCHEMBL6181563 | 0.78 | ALDH1A1 (0.35) | — | |
| SCHEMBL3431989 | 0.77 | — | — | |
| SCHEMBL22314884 | 0.77 | — | — | |
| SCHEMBL16591014 | 0.77 | LMNA (0.43) | — | |
| SCHEMBL16081329 | 0.77 | LMNA (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170166584-A1 | TRIAZOLE ACC INHIBITORS AND USES THEREOF | Nimbus Apollo, Inc. | 2017-06-15 | — | — | US | disclosed |
| US-20170166583-A1 | ESTER ACC INHIBITORS AND USES THEREOF | Nimbus Apollo, Inc. | 2017-06-15 | — | — | US | disclosed |
| US-20170166582-A1 | PYRAZOLE ACC INHIBITORS AND USES THEREOF | Nimbus Apollo, Inc. | 2017-06-15 | — | — | US | disclosed |
| WO-2011116312-A1 | FATTY ACID MACROLIDE DERIVATIVES AND THEIR USES | CATABASIS PHARMACEUTICALS, INC. (US) | 2011-09-22 | — | — | WO | disclosed |