Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 13/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 13/20 | 0.43 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.43 |
| ▸ | PRCP | P42785 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3225930 | 1.00 | HCRTR1 (0.43) | HCRTR1HCRTR2AADATPRCPGRIN2B | |
| SCHEMBL3216300 | 0.94 | AADAT (0.43) | HCRTR1HCRTR2AADATPRCPGRIN2B | |
| SCHEMBL3216317 | 0.94 | AADAT (0.43) | HCRTR1HCRTR2AADATPRCPGRIN2B | |
| SCHEMBL20434106 | 0.87 | HCRTR1 (0.42) | HCRTR1HCRTR2 | |
| SCHEMBL10117332 | 0.85 | AADAT (0.43) | AADAT | |
| SCHEMBL750855 | 0.85 | HCRTR1 (0.46) | HCRTR1HCRTR2 | |
| SCHEMBL12969780 | 0.85 | HCRTR1 (0.46) | HCRTR1HCRTR2 | |
| SCHEMBL1293568 | 0.85 | HCRTR1 (0.44) | HCRTR1HCRTR2 | |
| SCHEMBL203117 | 0.85 | HCRTR1 (0.44) | HCRTR1HCRTR2 | |
| SCHEMBL2707099 | 0.85 | HCRTR1 (0.44) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9120779-B2 | Inhibitors of HCV NS5A | PRESIDIO PHARMACEUTICALS, INC. (US) | 2015-09-01 | — | — | US | disclosed |
| US-20110237579-A1 | INHIBITORS OF HCV NS5A | PRESIDIO PHARMACEUTICALS, INC. (US) | 2011-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110237579-A1 | INHIBITORS OF HCV NS5A | MAVS, HAVCR2, EIF2AK2 | HCRTR1 4309/4885HCRTR2 4576/4885AADAT 3791/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.