Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 4/20 | 0.55 |
| ▸ | SYNJ2 | O15056 | 2/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.31 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.31 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.31 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.31 |
| ▸ | F3 | P13726 | 3/20 | 0.31 |
| ▸ | STAT3 | P40763 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16063114 | 1.00 | TYR (0.55) | TYRSYNJ2HSD11B1HSD11B2PSEN1 | |
| SCHEMBL14446474 | 0.80 | TYR (0.82) | TYRSYNJ2PSEN1PSEN2APH1B | |
| SCHEMBL20636509 | 0.80 | TYR (0.82) | TYRSYNJ2PSEN1PSEN2APH1B | |
| SCHEMBL15826747 | 0.80 | TYR (0.82) | TYRSYNJ2PSEN1PSEN2APH1B | |
| SCHEMBL17479915 | 0.80 | TYR (0.82) | TYRSYNJ2PSEN1PSEN2APH1B | |
| SCHEMBL12303842 | 0.80 | TYR (0.82) | TYRSYNJ2PSEN1PSEN2APH1B | |
| SCHEMBL19647513 | 0.80 | TYR (0.82) | TYRSYNJ2PSEN1PSEN2APH1B | |
| SCHEMBL14217990 | 0.80 | TYR (0.82) | TYRSYNJ2PSEN1PSEN2APH1B | |
| SCHEMBL12764257 | 0.80 | TYR (0.82) | TYRSYNJ2PSEN1PSEN2APH1B | |
| SCHEMBL30542251 | 0.80 | TYR (0.82) | TYRSYNJ2PSEN1PSEN2APH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110218161-A1 | CYCLOASTRAGENOL MONOGLUCOSIDE, PREPARATION, PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF | TIANJIN INSTITUTE OF PHARMACEUTICAL RESEARCH (CN) | 2011-09-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110218161-A1 | CYCLOASTRAGENOL MONOGLUCOSIDE, PREPARATION, PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF | CTSG, AGT, GCG | TYR 2162/4885SYNJ2 3532/4885HSD11B1 93/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.