SCHEMBL14446474

SCHEMBL14446474

CC(C)(O)[C@@H]1CC[C@](C)([C@H]2[C@@H](O)C[C@@]3(C)[C@@H]4C[C@H](OC5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)[C@H]5C(C)(C)[C@@H](O)CC[C@@]56C[C@@]46CC[C@]23C)O1

nearest known ligand 0.82

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ TYR P14679 4/20 0.82
▸ SYNJ2 O15056 2/20 0.36
▸ F3 P13726 3/20 0.33
▸ PRKAG1 P54619 3/20 0.33
▸ PRKAA2 P54646 3/20 0.33
▸ PRKAB1 Q9Y478 3/20 0.33
▸ SELP P16109 1/20 0.32
▸ STAT3 P40763 1/20 0.32
▸ PPARG P37231 1/20 0.32
▸ PSEN1 P49768 1/20 0.31
▸ PSEN2 P49810 1/20 0.31
▸ APH1B Q8WW43 1/20 0.31
▸ NCSTN Q92542 1/20 0.31
▸ APH1A Q96BI3 1/20 0.31
▸ PSENEN Q9NZ42 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9913456 1.00 TYR (0.82) TYRSYNJ2F3PRKAG1PRKAA2
SCHEMBL12303842 1.00 TYR (0.82) TYRSYNJ2F3PRKAG1PRKAA2
SCHEMBL30542251 1.00 TYR (0.82) TYRSYNJ2F3PRKAG1PRKAA2
SCHEMBL17479915 1.00 TYR (0.82) TYRSYNJ2F3PRKAG1PRKAA2
SCHEMBL15826747 1.00 TYR (0.82) TYRSYNJ2F3PRKAG1PRKAA2
SCHEMBL14217990 1.00 TYR (0.82) TYRSYNJ2F3PRKAG1PRKAA2
SCHEMBL12764257 1.00 TYR (0.82) TYRSYNJ2F3PRKAG1PRKAA2
SCHEMBL19647513 1.00 TYR (0.82) TYRSYNJ2F3PRKAG1PRKAA2
SCHEMBL20636509 1.00 TYR (0.82) TYRSYNJ2F3PRKAG1PRKAA2
SCHEMBL9913455 0.95 TYR (0.74) TYRSYNJ2F3PRKAG1PRKAA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9248088-B2 Compositions and methods for skin conditioning TELOMERASE ACTIVATION SCIENCES, INC. (US) 2016-02-02 — — US disclosed
US-20150093455-A1 COMPOSITIONS AND METHODS FOR INCREASING TELOMERASE ACTIVITY HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (HK) 2015-04-02 — — US disclosed
US-20070154435-A1 Compositions and methods for skin conditioning TELOMERASE ACTIVATION SCIENCES, INC. 2007-07-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150093455-A1 COMPOSITIONS AND METHODS FOR INCREASING TELOMERASE ACTIVITY TERT, TERF2, POT1 TYR 307/4885SYNJ2 3745/4885F3 435/4885
US-20070154435-A1 Compositions and methods for skin conditioning CUTA, ACOX3, AREG TYR 2369/4885SYNJ2 1960/4885F3 1170/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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