Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 11/20 | 0.58 |
| ▸ | HTR2B | P41595 | 10/20 | 0.58 |
| ▸ | HTR2A | P28223 | 9/20 | 0.58 |
| ▸ | ADCY6 | O43306 | 1/20 | 0.32 |
| ▸ | ADCY3 | O60266 | 1/20 | 0.32 |
| ▸ | ADCY9 | O60503 | 1/20 | 0.32 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.32 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.32 |
| ▸ | ADCY7 | P51828 | 1/20 | 0.32 |
| ▸ | ADCY2 | Q08462 | 1/20 | 0.32 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.32 |
| ▸ | ADCY4 | Q8NFM4 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12105398 | 0.69 | HTR2C (0.50) | HTR2CHTR2BHTR2AADCY6ADCY3 | |
| SCHEMBL15502922 | 0.65 | HTR2C (0.50) | HTR2CHTR2BHTR2AHTR7 | |
| SCHEMBL2310044 | 0.65 | HTR2B (0.39) | HTR2CHTR2BHTR2AADCY6ADCY3 | |
| SCHEMBL12579957 | 0.62 | HTR2C (0.62) | HTR2CHTR2BHTR2A | |
| SCHEMBL15503164 | 0.62 | HTR2C (0.47) | HTR2CHTR2BHTR2AADCY6ADCY3 | |
| SCHEMBL12107404 | 0.61 | ADRA2A (0.37) | HTR2CHTR2BHTR2AADCY6ADCY3 | |
| SCHEMBL12107392 | 0.61 | ALDH1A1 (0.37) | HTR2CHTR2BHTR2AADCY6ADCY3 | |
| SCHEMBL12107510 | 0.61 | KDM4E (0.33) | HTR2CHTR2BHTR2AADCY6ADCY3 | |
| Bromide SCHEMBL2310713 | 0.61 | HTR2C (0.46) | HTR2CHTR2BHTR2AADCY6ADCY3 | |
| SCHEMBL2307639 | 0.61 | KCNH2 (0.41) | HTR2CHTR2BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011111817-A1 | BENZAZEPINE COMPOUND | アステラス製薬株式会社 (JP) | 2011-09-15 | — | — | WO | disclosed |