Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 4/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | MYC | P01106 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12333415 | 0.91 | MAPT (0.55) | MAPTALOX15SIRT2KDM4EPOLB | |
| SCHEMBL12109319 | 0.85 | MAPT (0.81) | MAPTALOX15SIRT2KDM4EPOLB | |
| SCHEMBL28649151 | 0.82 | MAPT (0.81) | MAPTALOX15SIRT2KDM4EPOLB | |
| SCHEMBL13224505 | 0.81 | MAPT (0.89) | MAPTALOX15SIRT2KDM4EPOLB | |
| SCHEMBL12109338 | 0.79 | MAPT (0.69) | MAPTALOX15SIRT2KDM4EPOLB | |
| SCHEMBL1301699 | 0.79 | MAPT (0.69) | MAPTALOX15SIRT2KDM4EPOLB | |
| SCHEMBL783331 | 0.78 | MAPT (0.57) | MAPTALOX15SIRT2KDM4EPOLB | |
| SCHEMBL2787546 | 0.78 | MAPT (0.56) | MAPTALOX15SIRT2KDM4EPOLB | |
| SCHEMBL13895944 | 0.77 | NR4A2 (0.60) | MAPTALOX15KDM4EPOLBATM | |
| SCHEMBL21763341 | 0.76 | HDAC4 (0.34) | MAPTALOX15SIRT2KDM4EATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170155062-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2017-06-01 | — | — | US | disclosed |
| US-20120319052-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2012-12-20 | — | — | US | disclosed |
| US-20120319052-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2012-12-20 | — | — | US | disclosed |
| WO-2011107186-A2 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2011-09-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170155062-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | CYP1B1, CYP1A1, CYP2E1 | MAPT 2304/4885ALOX15 1353/4885SIRT2 1114/4885 |
| US-20120319052-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | CYP1B1, CYP1A1, CYP2E1 | MAPT 2304/4885ALOX15 1353/4885SIRT2 1114/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.