Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.69 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.69 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | AURKA | O14965 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17617073 | 0.95 | MAPT (0.76) | MAPTALOX15SLC6A3KDM4EALDH1A1 | |
| SCHEMBL12109319 | 0.92 | MAPT (0.81) | MAPTALOX15SLC6A3KDM4EHPGD | |
| SCHEMBL28649151 | 0.89 | MAPT (0.81) | MAPTALOX15SLC6A3KDM4EALDH1A1 | |
| SCHEMBL13224505 | 0.87 | MAPT (0.89) | MAPTALOX15KDM4EALDH1A1HPGD | |
| SCHEMBL12109338 | 0.85 | MAPT (0.69) | MAPTALOX15SLC6A3KDM4EALDH1A1 | |
| SCHEMBL31914 | 0.82 | MAPT (1.00) | MAPTALOX15KDM4EALDH1A1HPGD | |
| SCHEMBL28658698 | 0.81 | MAPT (0.78) | MAPTALOX15KDM4EALDH1A1RAB9A | |
| SCHEMBL13832955 | 0.80 | MAPT (0.76) | MAPTALOX15SLC6A3KDM4EALDH1A1 | |
| SCHEMBL22452889 | 0.80 | MAPT (0.76) | MAPTALOX15KDM4EALDH1A1HPGD | |
| SCHEMBL22853361 | 0.80 | MAPT (0.76) | MAPTALOX15SLC6A3KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9034485-B2 | Compounds for electronic devices | MERCK PATENT GMBH (DE) | 2015-05-19 | — | — | US | disclosed |
| US-9034485-B2 | Compounds for electronic devices | MERCK PATENT GMBH (DE) | 2015-05-19 | — | — | US | disclosed |
| US-9034485-B2 | Compounds for electronic devices | MERCK PATENT GMBH (DE) | 2015-05-19 | — | — | US | disclosed |
| US-20110266533-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2011-11-03 | — | — | US | disclosed |
| US-20110266533-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2011-11-03 | — | — | US | disclosed |
| US-20110266533-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2011-11-03 | — | — | US | disclosed |
| WO-2010083871-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2010-07-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110266533-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | SLCO2A1, SLC40A1, TOE1 | MAPT 1198/4885ALOX15 874/4885SLC6A3 174/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.