Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 1/20 | 0.52 |
| ▸ | ITGA1 | P56199 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | BCL2 | P10415 | 1/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.43 |
| ▸ | LOX | P28300 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12334072 | 0.89 | CCKBR (0.60) | CCKBRKMT2AMEN1PKMHPGD | |
| SCHEMBL12334073 | 0.87 | CCKBR (0.49) | CCKBRKMT2AMEN1PKMHPGD | |
| SCHEMBL12334053 | 0.85 | NR1H3 (0.54) | CCKBRKMT2AMEN1PKMHPGD | |
| SCHEMBL12334668 | 0.83 | CCKBR (0.46) | CCKBRKMT2AMEN1PKMHPGD | |
| SCHEMBL9997173 | 0.82 | CCKBR (0.54) | CCKBRKMT2AMEN1PKMHPGD | |
| SCHEMBL8013271 | 0.80 | CCKBR (0.49) | CCKBRKMT2AMEN1HPGDMAPT | |
| SCHEMBL7460244 | 0.80 | CCKBR (0.50) | CCKBRKMT2AMEN1HPGDMAPT | |
| SCHEMBL8033818 | 0.79 | HPGD (0.54) | CCKBRKMT2AMEN1HPGDMAPT | |
| SCHEMBL15079960 | 0.79 | CCKBR (0.51) | CCKBRKMT2AMEN1PKMMAPT | |
| SCHEMBL7451657 | 0.79 | MEN1 (0.51) | CCKBRKMT2AMEN1PKMHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011115892-A1 | MODULATORS OF THE RETINOIC ACID RECEPTOR-RELATED ORPHAN RECEPTORS | GRIFFIN PATRICK R (US) | 2011-09-22 | — | — | WO | disclosed |