Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | BCL2 | P10415 | 1/20 | 0.47 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.47 |
| ▸ | LOX | P28300 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8033818 | 0.83 | HPGD (0.54) | CCKBRMEN1KMT2AHPGDBCL2 | |
| SCHEMBL7451657 | 0.83 | MEN1 (0.51) | CCKBRMEN1KMT2AHPGDBCL2 | |
| Hydrochloric Acid SCHEMBL28187724 | 0.82 | HPGD (0.52) | CCKBRMEN1KMT2AHPGDBCL2 | |
| SCHEMBL1742818 | 0.82 | HPGD (0.52) | CCKBRMEN1KMT2AHPGDBCL2 | |
| SCHEMBL13881587 | 0.82 | MEN1 (0.54) | CCKBRMEN1KMT2AHPGDBCL2 | |
| SCHEMBL1742958 | 0.82 | HPGD (0.52) | CCKBRMEN1KMT2AHPGDLOX | |
| SCHEMBL12334602 | 0.80 | CCKBR (0.52) | CCKBRMEN1KMT2AHPGDBCL2 | |
| SCHEMBL5017241 | 0.80 | LOX (0.45) | CCKBRMEN1KMT2AHPGDBCL2 | |
| SCHEMBL12334072 | 0.79 | CCKBR (0.60) | CCKBRMEN1KMT2AHPGDBCL2 | |
| SCHEMBL14519924 | 0.79 | MEN1 (0.52) | CCKBRMEN1KMT2AHPGDBCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1129108-A4 | CASPASES AND APOPTOSIS | SMITHKLINE BEECHAM CORP (US) | 2002-01-09 | — | — | EP | disclosed |
| EP-1129108-A1 | CASPASES AND APOPTOSIS | SmithKline Beecham Corporation (US) | 2001-09-05 | — | — | EP | disclosed |
| WO-2000020440-A1 | CASPASES AND APOPTOSIS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-04-13 | — | — | WO | disclosed |