Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9165049 | 0.84 | LMNA (0.48) | LMNAKMT2AMEN1MAPTKDM4E | |
| SCHEMBL4403134 | 0.84 | POLB (0.47) | LMNAKMT2AMEN1MAPTKDM4E | |
| SCHEMBL26717934 | 0.81 | POLB (0.41) | LMNAKMT2AMEN1MAPTKDM4E | |
| SCHEMBL16653023 | 0.80 | POLB (0.45) | LMNAKMT2AMEN1MAPTKDM4E | |
| SCHEMBL471978 | 0.79 | NPSR1 (0.49) | LMNAKMT2AMEN1MAPTKDM4E | |
| SCHEMBL26717933 | 0.79 | KMT2A (0.44) | LMNAKMT2AMEN1MAPTKDM4E | |
| SCHEMBL21066306 | 0.79 | MEN1 (0.44) | LMNAKMT2AMEN1MAPTKDM4E | |
| SCHEMBL13454337 | 0.78 | NPSR1 (0.46) | LMNAKMT2AMEN1MAPTKDM4E | |
| SCHEMBL13231704 | 0.78 | LMNA (0.50) | LMNAKMT2AMEN1MAPTKDM4E | |
| SCHEMBL4401116 | 0.78 | LMNA (0.40) | LMNAKMT2AMEN1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2366752-A2 | New materials for electroluminescence and use of same | Merck Patent GmbH (DE) | 2011-09-21 | — | — | EP | disclosed |