SCHEMBL21066306

SCHEMBL21066306

Cc1cc(P(=O)(c2ccccc2)c2ccccc2)ccc1Br

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 8/20 0.44
KMT2A Q03164 8/20 0.44
RAB9A P51151 6/20 0.44
MAPT P10636 5/20 0.44
LMNA P02545 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
KDM4E B2RXH2 2/20 0.44
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
NPC1 O15118 4/20 0.40
POLB P06746 3/20 0.40
ALDH1A1 P00352 1/20 0.40
RECQL P46063 1/20 0.38
ESR1 P03372 1/20 0.37
NFKB1 P19838 1/20 0.37
NFKB2 Q00653 1/20 0.37
RELA Q04206 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21275949 0.87 RAB9A (0.49) MEN1KMT2ARAB9AMAPTLMNA
SCHEMBL9165049 0.82 LMNA (0.48) MEN1KMT2ARAB9AMAPTLMNA
SCHEMBL12336802 0.79 LMNA (0.46) MEN1KMT2ARAB9AMAPTLMNA
SCHEMBL26717933 0.78 KMT2A (0.44) MEN1KMT2ARAB9AMAPTLMNA
SCHEMBL1242127 0.76 KMT2A (0.41) MEN1KMT2ARAB9AMAPTLMNA
SCHEMBL13231704 0.76 LMNA (0.50) MEN1KMT2ARAB9AMAPTLMNA
Triphenylphosphine Oxide SCHEMBL29014411 0.75 ACHE (0.53) MEN1KMT2ARAB9AMAPTLMNA
SCHEMBL5436616 0.74 LMNA (0.60) MEN1KMT2AMAPTLMNAALDH1A1
SCHEMBL5439069 0.74 LMNA (0.60) MEN1KMT2AMAPTLMNAALDH1A1
SCHEMBL132983 0.74 LMNA (0.60) MEN1KMT2AMAPTLMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109970791-B Indenotriphenylene derivative and organic electroluminescent device using the same 机光科技股份有限公司 2022-07-22 CN disclosed
US-10428269-B2 Indenotriphenylene derivative and organic electroluminescence device using the same LUMINESCENCE TECHNOLOGY CORP. (TW) 2019-10-01 US disclosed
US-20190194534-A1 INDENOTRIPHENYLENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME LUMINESCENCE TECHNOLOGY CORPORATION (TW) 2019-06-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190194534-A1 INDENOTRIPHENYLENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME ICMT, INCENP, ITPA MEN1 2750/4885KMT2A 3084/4885RAB9A 1904/4885
US-10428269-B2 Indenotriphenylene derivative and organic electroluminescence device using the same ICMT, INCENP, ITPA MEN1 2750/4885KMT2A 3084/4885RAB9A 1904/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.