Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.44 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.44 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.44 |
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PLK1 | P53350 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | CLK1 | P49759 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27309407 | 0.85 | MGAM (0.44) | MGAMMEN1KMT2AALDH1A1HTT | |
| SCHEMBL626577 | 0.84 | MGAM (0.61) | MGAMALDH1A1ALOX15MAPTKDM4E | |
| SCHEMBL30628188 | 0.82 | F7 (0.47) | MKNK2MGAMALDH1A1MAPTKDM4E | |
| Hydrochloric Acid SCHEMBL7010609 | 0.82 | MGAM (0.59) | MGAMMEN1KMT2AALDH1A1ALOX15 | |
| SCHEMBL1198665 | 0.82 | F7 (0.47) | MKNK2MGAMALDH1A1MAPTKDM4E | |
| SCHEMBL31042186 | 0.81 | ALOX15 (0.59) | MEN1KMT2ATGFBR1ALDH1A1HTT | |
| SCHEMBL5778688 | 0.81 | ALOX15 (0.59) | MEN1KMT2ATGFBR1ALDH1A1HTT | |
| SCHEMBL29812385 | 0.81 | PLK1 (0.59) | MKNK2MEN1KMT2AALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL14966719 | 0.81 | F7 (0.46) | MKNK2MGAMALDH1A1MAPTKDM4E | |
| Hydrochloric Acid SCHEMBL27822372 | 0.80 | PLK1 (0.57) | MKNK2MEN1KMT2AALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3419972-B1 | GLYCOSIDASE INHIBITORS | ASCENEURON SA (CH) | 2023-07-26 | — | — | EP | disclosed |
| EP-3810592-A1 | OGA INHIBITOR COMPOUNDS | Janssen Pharmaceutica NV (BE) | 2021-04-28 | — | — | EP | disclosed |
| US-10556902-B2 | Glycosidase inhibitors | ASCENEURON SA (CH) | 2020-02-11 | — | — | US | disclosed |
| WO-2019243525-A1 | OGA INHIBITOR COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2019-12-26 | — | — | WO | disclosed |
| US-20190055239-A1 | GLYCOSIDASE INHIBITORS | ASCENEURON SA (CH) | 2019-02-21 | — | — | US | disclosed |
| EP-3419972-A1 | GLYCOSIDASE INHIBITORS | Asceneuron SA (CH) | 2019-01-02 | — | — | EP | disclosed |
| WO-2017144639-A1 | GLYCOSIDASE INHIBITORS | ASCENEURON S. A. (CH) | 2017-08-31 | — | — | WO | disclosed |
| US-8461083-B2 | Herbicidal compounds | SYNGENTA LIMITED (GB) | 2013-06-11 | — | — | US | disclosed |
| EP-2265120-B1 | HERBICIDAL COUMPOUNDS | SYNGENTA LTD (GB) | 2012-03-07 | — | — | EP | disclosed |
| US-20110021352-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-01-27 | — | — | US | disclosed |
| EP-2265120-A1 | HERBICIDAL COUMPOUNDS | Syngenta Limited (GB) | 2010-12-29 | — | — | EP | disclosed |
| WO-2009115788-A1 | HERBICIDAL COUMPOUNDS | SYNGENTA LIMITED (GB) | 2009-09-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10556902-B2 | Glycosidase inhibitors | ENGASE, GAA, GLA | MAP4K4 4401/4885CSNK1G2 1465/4885CLK4 3803/4885 |
| US-20110021352-A1 | HERBICIDAL COMPOUNDS | RDX, NQO2, DDT | MAP4K4 3864/4885CSNK1G2 2832/4885CLK4 2351/4885 |
| US-20190055239-A1 | GLYCOSIDASE INHIBITORS | ENGASE, GAA, GLA | MAP4K4 4401/4885CSNK1G2 1465/4885CLK4 3803/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.