Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.45 |
| ▸ | GABRP | O00591 | 2/20 | 0.43 |
| ▸ | GABRD | O14764 | 2/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7010609 | 0.98 | MGAM (0.59) | MGAMALDH1A1ALOX15HPGDHSD17B10 | |
| SCHEMBL27309407 | 0.87 | MGAM (0.44) | MGAMALDH1A1ALOX15HPGDHSD17B10 | |
| SCHEMBL1198665 | 0.84 | F7 (0.47) | MGAMALDH1A1MAPTPSMD14NPC1 | |
| SCHEMBL123372 | 0.84 | MAP4K4 (0.44) | MGAMALDH1A1ALOX15MAPTNPC1 | |
| SCHEMBL30628188 | 0.84 | F7 (0.47) | MGAMALDH1A1MAPTPSMD14NPC1 | |
| SCHEMBL27822223 | 0.83 | MGAM (0.44) | MGAMALDH1A1ALOX15HPGDHSD17B10 | |
| Quinoline SCHEMBL28116161 | 0.83 | MGAM (0.84) | MGAMALDH1A1ALOX15GAAMAPT | |
| Hydrochloric Acid SCHEMBL14966719 | 0.82 | F7 (0.46) | MGAMALDH1A1MAPTPSMD14NPC1 | |
| Benzoic Acid SCHEMBL28624673 | 0.80 | NAPRT (0.61) | MGAMALDH1A1ALOX15HPGDHSD17B10 | |
| SCHEMBL31042186 | 0.80 | ALOX15 (0.59) | ALDH1A1ALOX15GAAMAPTPSMD14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 311 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113825756-A | Substituted polycyclic carboxylic acids, analogs thereof, and methods of use thereof | 爱彼特生物制药公司 | 2021-12-21 | — | — | CN | claimed |
| CN-107820496-B | Tetracyclic 4-oxo-pyridine-3-carboxylic acid derivatives for the treatment and prevention of hepatitis B virus infections | 豪夫迈·罗氏有限公司 | 2020-11-03 | — | — | CN | claimed |
| CN-110475777-A | For treating and preventing new pyrido [2,3-b] benzazolyl compounds of bacterium infection | HOFFMANN LA ROCHE | 2019-11-19 | — | — | CN | claimed |
| CN-106632317-A | 1,4-dihydro-naphthyridine derivative and pharmaceutical composition and application thereof | 江苏欧威医药有限公司 | 2017-05-10 | — | — | CN | claimed |
| CN-104203945-B | 1, 4-dihydro-naphthyridine derivatives, pharmaceutical compositions and uses thereof | 江苏欧威医药有限公司 | 2017-01-18 | — | — | CN | claimed |
| CN-105481851-A | Hexahydrobenzonaphthyridine-type optically active compound and pharmaceutical use thereof | ZHAOLONG GONG | 2016-04-13 | — | — | CN | claimed |
| CN-104203945-A | 1, 4-dihydro-naphthyridine derivatives, pharmaceutical compositions and uses thereof | JIANGSU SIMOVAY PHARMACEUTICAL CO LTD | 2014-12-10 | — | — | CN | claimed |
| CN-103889414-A | pharmaceutical composition | RAQUALIA PHARMA INC | 2014-06-25 | — | — | CN | claimed |
| CN-102574840-B | R-7-(3-aminomethyl-4-methoxyimino-3-methyl-pyrrolidin-1-yl)-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid and l-aspartic acid salt, process for the preparation thereof and pharmaceutical composition comprising the same | ARMED INC | 2014-05-28 | — | — | CN | claimed |
| CN-102574840-A | R-7-(3-aminomethyl-4-methoxyimino-3-methyl-pyrrolidin-1-yl)-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid and l-aspartic acid salt, process for the preparation thereof and pharmaceutical composition comprising the same | ARIMED INC | 2012-07-11 | — | — | CN | claimed |
| CN-1150181-C | Substituted benzopyran analogs for treatment of inflammation | GD | 2004-05-19 | — | — | CN | claimed |
| WO-2004019940-A1 | METHOD OF PREVENTING OR TREATING ATHEROSCLEROSIS OR RESTENOSIS | PHARMACIA & UPJOHN COMPANY (US) | 2004-03-11 | — | — | WO | claimed |
| WO-2004014367-A2 | USE OF AN AMYLOID BETA VACCINATION IN COMBINATION WITH A SELECTIVE COX-2 INHIBITOR FOR THE TREATMENT OF ALZHEIMER'S DISEASE | PHARMACIA CORPORATION (US) | 2004-02-19 | — | — | WO | claimed |
| WO-2004004833-A1 | USE OF CYCLOOXYGENASE-2 SELECTIVE INHIBITORS AND THROMBOLYTIC AGENTS FOR THE TREATMENT OR PREVENTION OF A VASO-OCCLUSIVE EVENT | PHARMACIA CORPORATION (US) | 2004-01-15 | — | — | WO | claimed |
| WO-2003015608-A2 | COMBINATION THERAPY FOR THE TREATMENT OF CANCER | SUGEN, INC. (US) | 2003-02-27 | — | — | WO | claimed |
| CN-1377347-A | Pharmaceutically active sulfonamide derivatives | APPLIED RESEARCH SYSTEMS (NL) | 2002-10-30 | — | — | CN | claimed |
| EP-1230235-A1 | COMPOUNDS WITH ANTIBACTERIAL AND ANTIPARASITIC PROPERTIES | New Pharma Research Sweden AB (SE) | 2002-08-14 | — | — | EP | claimed |
| WO-2001036408-A1 | COMPOUNDS WITH ANTIBACTERIAL AND ANTIPARASITIC PROPERTIES | NEW PHARMA RESEARCH SWEDEN AB (SE) | 2001-05-25 | — | — | WO | claimed |
| CN-1257489-A | Substituted benzopyran derivatives for the treatment of inflammation | SEARLE & CO (US) | 2000-06-21 | — | — | CN | claimed |
| WO-1995007909-A1 | ALKYL-1-ALKYL-4-HYDROXY-2-OXO-1,8-NAPHTHYRIDINE-3-CARBOXYLATES AS ANTI-RHEUMATIC AGENTS | KNOLL AG (DE) | 1995-03-23 | — | — | WO | claimed |