Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINA3 | P01011 | 1/20 | 0.48 |
| ▸ | BTN3A1 | O00481 | 9/20 | 0.42 |
| ▸ | POLB | P06746 | 4/20 | 0.38 |
| ▸ | ADCY2 | Q08462 | 1/20 | 0.35 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | POLA1 | P09884 | 2/20 | 0.34 |
| ▸ | POLG | P54098 | 2/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.34 |
| ▸ | FAP | Q12884 | 1/20 | 0.34 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2607065 | 0.87 | SERPINA3 (0.46) | SERPINA3BTN3A1POLBADCY2SLC22A6 | |
| SCHEMBL12339260 | 0.87 | SERPINA3 (0.48) | SERPINA3BTN3A1POLBADCY2SLC22A6 | |
| SCHEMBL12339226 | 0.85 | POLB (0.57) | SERPINA3BTN3A1POLBADCY2 | |
| SCHEMBL12339261 | 0.85 | SERPINA3 (0.44) | SERPINA3BTN3A1POLBADCY2 | |
| SCHEMBL12339253 | 0.84 | POLB (0.53) | SERPINA3POLBPOLA1POLGHPRT1 | |
| SCHEMBL21577310 | 0.84 | FGFR1 (0.53) | SERPINA3BTN3A1ADCY2SLC22A6FGFR1 | |
| SCHEMBL12339258 | 0.84 | FGFR1 (0.53) | SERPINA3BTN3A1ADCY2SLC22A6FGFR1 | |
| SCHEMBL19370539 | 0.84 | FGFR1 (0.53) | SERPINA3BTN3A1ADCY2SLC22A6FGFR1 | |
| SCHEMBL2734837 | 0.81 | POLB (0.49) | SERPINA3POLBSLC22A6FGFR1POLA1 | |
| SCHEMBL2606867 | 0.81 | BTN3A1 (0.42) | SERPINA3BTN3A1POLBSLC22A6FGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8268802-B2 | Anti-proliferative compounds, compositions, and methods of use thereof | GILEAD SCIENCES, INC. (US) | 2012-09-18 | — | — | US | disclosed |