Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | MYC | P01106 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL48126 | 0.88 | CYP3A4 (0.45) | TNKS2TAAR1HTTCYP3A4SMN1; SMN2 | |
| SCHEMBL47985 | 0.85 | HTT (0.58) | TNKS2HTTCYP3A4SMN1; SMN2MAPT | |
| SCHEMBL48204 | 0.85 | HTR2A (0.47) | TNKS2TAAR1HTTCYP3A4SMN1; SMN2 | |
| SCHEMBL48163 | 0.82 | HTT (0.58) | TNKS2HTTCYP3A4ALOX5SMN1; SMN2 | |
| SCHEMBL15562566 | 0.78 | TAAR1 (0.53) | TNKS2TAAR1CYP3A4ALOX5ALDH1A1 | |
| SCHEMBL12341799 | 0.76 | SMN1; SMN2 (0.49) | TNKS2HTTCYP3A4ALOX5SMN1; SMN2 | |
| SCHEMBL11154634 | 0.75 | HTT (0.64) | HTTCYP3A4SMN1; SMN2LMNAMAPT | |
| SCHEMBL1753958 | 0.73 | HTT (0.52) | TAAR1HTTCYP3A4SMN1; SMN2LMNA | |
| SCHEMBL47914 | 0.73 | APLNR (0.50) | ALDH1A1KMT2AMEN1POLB | |
| SCHEMBL48106 | 0.73 | MTNR1A (0.59) | TAAR1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE43676-E1 | Alkyl ether derivatives or salts thereof | TOYAMA CHEMICAL CO., LTD. (JP) | 2012-09-18 | — | — | US | disclosed |