Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.54 |
| ▸ | RAB9A | P51151 | 7/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA7 | P43166 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | STAT1 | P42224 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1233875 | 0.85 | NPC1 (0.50) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL30645374 | 0.84 | NPC1 (0.49) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL17987760 | 0.84 | NPC1 (0.49) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL3437613 | 0.84 | NPC1 (0.63) | NPC1RAB9AMAPTALDH1A1KDM4E | |
| SCHEMBL2247476 | 0.84 | NPC1 (0.59) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL1458735 | 0.82 | ALDH1A1 (0.58) | NPC1RAB9AMAPTALDH1A1KDM4E | |
| SCHEMBL24307522 | 0.80 | NPC1 (0.55) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL24920215 | 0.80 | NPC1 (0.54) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL14473945 | 0.78 | ALDH1A1 (0.61) | NPC1RAB9AMAPTALDH1A1KDM4E | |
| SCHEMBL14473944 | 0.78 | ALDH1A1 (0.61) | NPC1RAB9AMAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2011037776-A | QUINOXALINE COMPOUND OR SALT THEREOF AND INDUSTRIAL BACTERICIDAL COMPOSITION | JAPAN ENVIRO CHEMICALS LTD | 2011-02-24 | — | — | JP | disclosed |