Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.59 |
| ▸ | RAB9A | P51151 | 8/20 | 0.59 |
| ▸ | CA12 | O43570 | 2/20 | 0.56 |
| ▸ | CA1 | P00915 | 2/20 | 0.56 |
| ▸ | CA2 | P00918 | 2/20 | 0.56 |
| ▸ | CA7 | P43166 | 2/20 | 0.56 |
| ▸ | CA9 | Q16790 | 2/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | STAT1 | P42224 | 1/20 | 0.52 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.51 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3437613 | 0.90 | NPC1 (0.63) | NPC1RAB9ACA12CA1CA2 | |
| SCHEMBL1458735 | 0.87 | ALDH1A1 (0.58) | NPC1RAB9ACA12CA1CA2 | |
| SCHEMBL12366661 | 0.87 | NPC1 (0.48) | NPC1RAB9ACA12CA1CA2 | |
| SCHEMBL20475327 | 0.85 | RAB9A (0.52) | NPC1RAB9ACA12CA1CA2 | |
| SCHEMBL1234503 | 0.84 | NPC1 (0.54) | NPC1RAB9ACA12CA1CA2 | |
| SCHEMBL20475262 | 0.84 | NPC1 (0.51) | NPC1RAB9ACA12CA1CA2 | |
| SCHEMBL14473944 | 0.83 | ALDH1A1 (0.61) | NPC1RAB9ACA12CA1CA2 | |
| SCHEMBL14473945 | 0.83 | ALDH1A1 (0.61) | NPC1RAB9ACA12CA1CA2 | |
| SCHEMBL20475368 | 0.83 | RAB9A (0.57) | NPC1RAB9AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL2244311 | 0.82 | ALDH1A1 (0.57) | NPC1RAB9AALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7994423-B2 | Charge-transport materials, methods of fabrication thereof, and methods of use thereof | GEORGIA TECH RESEARCH CORPORATION (US) | 2011-08-09 | — | — | US | disclosed |
| US-7994423-B2 | Charge-transport materials, methods of fabrication thereof, and methods of use thereof | GEORGIA TECH RESEARCH CORPORATION (US) | 2011-08-09 | — | — | US | disclosed |
| US-20090065057-A1 | Charge-Transport Materials, Methods of Fabrication Thereof, and Methods of Use Thereof | GEORGIA TECH RESEARCH CORPORATION | 2009-03-12 | — | — | US | disclosed |
| US-20090065057-A1 | Charge-Transport Materials, Methods of Fabrication Thereof, and Methods of Use Thereof | GEORGIA TECH RESEARCH CORPORATION | 2009-03-12 | — | — | US | disclosed |
| WO-2005123737-A2 | CHARGE-TRANSPORT MATERIALS, METHODS OF FABRICATION THEREOF, AND METHODS OF USE THEREOF | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2005-12-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090065057-A1 | Charge-Transport Materials, Methods of Fabrication Thereof, and Methods of Use Thereof | SLC9A3, SLC18A2, SLC9A2 | NPC1 227/4885RAB9A 530/4885CA12 228/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.