SCHEMBL123459

SCHEMBL123459

COc1cc2c(cc1OC)[C@@H]1Cc3cc(O)c(O)cc3CN1CC2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
DRD1 P21728 11/20 1.00
DRD2 P14416 14/20 0.95
RAD52 P43351 1/20 0.86
DRD5 P21918 2/20 0.85
DRD3 P35462 2/20 0.85
HTR1A P08908 1/20 0.67
F3 P13726 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14235276 1.00 DRD1 (1.00) DRD1DRD2RAD52DRD5DRD3
SCHEMBL15624986 0.97 DRD2 (1.00) DRD1DRD2RAD52DRD5DRD3
SCHEMBL910400 0.96 DRD2 (1.00) DRD1DRD2RAD52DRD5DRD3
SCHEMBL29999733 0.96 DRD2 (1.00) DRD1DRD2RAD52DRD5DRD3
SCHEMBL30473248 0.96 DRD2 (1.00) DRD1DRD2RAD52DRD5DRD3
SCHEMBL29999626 0.96 DRD2 (1.00) DRD1DRD2RAD52DRD5DRD3
SCHEMBL910848 0.96 DRD2 (1.00) DRD1DRD2RAD52DRD5DRD3
Discretine SCHEMBL29408007 0.96 DRD2 (1.00) DRD1DRD2RAD52DRD5DRD3
SCHEMBL30473256 0.95 DRD2 (0.92) DRD1DRD2RAD52DRD5DRD3
SCHEMBL14234520 0.93 DRD1 (0.97) DRD1DRD2RAD52DRD5DRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 345 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118090959-A Method for identifying coptis chinensis varieties based on broad-range targeted metabonomics 湖北中医药大学 2024-05-28 CN claimed
US-20230172916-A1 COMPOSITION COMPRISING AT LEAST ONE PROTOBERBERINE ALKALOID AND METHOD FOR MANUFACTURING SAME ELEONOR (BE) 2023-06-08 US claimed
EP-4135666-A1 COMPOSITION COMPRISING AT LEAST ONE PROTOBERBERINE ALKALOID AND METHOD FOR MANUFACTURING SAME Eleonor (BE) 2023-02-22 EP claimed
WO-2021209623-A1 COMPOSITION COMPRISING AT LEAST ONE PROTOBERBERINE ALKALOID AND METHOD FOR MANUFACTURING SAME ELEONOR SPRL (BE) 2021-10-21 WO claimed
EP-3672575-A1 COMPOSITION COMPRISING AT LEAST ONE PROTOBERBERINE ALKALOID AND ITS PRODUCTION PROCESS Eleonor SPRL (BE) 2020-07-01 EP claimed
EP-3010893-B1 ARYLSULFIDE AND ARYLSULFOXIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES BAYER CROPSCIENCE AG (DE) 2019-10-02 EP claimed
EP-2731437-B1 ARTHROPOD PEST CONTROL COMPOSITION AND METHOD FOR CONTROLLING ARTHROPOD PESTS SUMITOMO CHEMICAL CO (JP) 2019-05-22 EP claimed
WO-2019038430-A1 COMPOSITION COMPRISING AT LEAST ONE PROTOBERBERINE ALKALOID AND ITS PRODUCTION PROCESS ELEONOR SPRL (BE) 2019-02-28 WO claimed
EP-3395171-A1 N-ARYLAMIDINE-SUBSTITUTED TRIFLUOROETHYLSULFIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES Bayer CropScience Aktiengesellschaft (DE) 2018-10-31 EP claimed
EP-3010889-B1 ARYLSULFIDE AND ARYLSULFOXIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES BAYER CROPSCIENCE AG (DE) 2018-10-03 EP claimed
EP-2935267-A1 ARYL SULFIDE DERIVATIVES AND ARYL SULFOXIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES Bayer CropScience AG (DE) 2015-10-28 EP claimed
WO-2014202505-A1 ARYL SULFIDE DERIVATIVES AND ARYL SULFOXIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES BAYER CROPSCIENCE AG (DE) 2014-12-24 WO claimed
WO-2014202510-A1 ARYL SULFIDE DERIVATIVES AND ARYL SULFOXIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES BAYER CROPSCIENCE AG (DE) 2014-12-24 WO claimed
EP-2793578-A1 N-ARYLAMIDINE-SUBSTITUTED TRIFLUOROETHYL SULFIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES Bayer CropScience AG (DE) 2014-10-29 EP claimed
EP-1722624-B1 METHOD FOR PREPARING TRANSGENIC PEPPER USING CALLUS INDUCTION NONGWOOBIO (KR) 2014-10-15 EP claimed
WO-2014095979-A1 ARYL SULFIDE DERIVATIVES AND ARYL SULFOXIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES BAYER CROPSCIENCE AG (DE) 2014-06-26 WO claimed
WO-2013092350-A1 N-ARYLAMIDINE-SUBSTITUTED TRIFLUOROETHYL SULFIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES BAYER CROPSCIENCE AG (DE) 2013-06-27 WO claimed
EP-2606726-A1 N-Arylamidine-substituted trifluoroethylsulfide derivatives as acaricides and insecticides Bayer CropScience AG (DE) 2013-06-26 EP claimed
WO-2012045680-A2 INSECTICIDAL AND FUNGICIDAL ACTIVE SUBSTANCE COMBINATIONS BAYER CROPSCIENCE AG (DE) 2012-04-12 WO claimed
EP-1744763-B1 SPINOSYNS FOR WOUND HEALING LILLY CO ELI (US) 2010-01-06 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230172916-A1 COMPOSITION COMPRISING AT LEAST ONE PROTOBERBERINE ALKALOID AND METHOD FOR MANUFACTURING SAME MANBA, CROCC, MAN2A1 DRD1 1370/4885DRD2 1092/4885RAD52 4417/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.