SCHEMBL29999733

SCHEMBL29999733

COc1cc2c(cc1O)CN1CCc3cc(OC)c(OC)cc3C1C2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 13/20 1.00
DRD1 P21728 11/20 1.00
DRD5 P21918 1/20 0.92
DRD3 P35462 1/20 0.92
RAD52 P43351 1/20 0.84
HTR1A P08908 1/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29999626 1.00 DRD2 (1.00) DRD2DRD1DRD5DRD3RAD52
Discretine SCHEMBL29408007 1.00 DRD2 (1.00) DRD2DRD1DRD5DRD3RAD52
SCHEMBL30473248 1.00 DRD2 (1.00) DRD2DRD1DRD5DRD3RAD52
SCHEMBL910400 1.00 DRD2 (1.00) DRD2DRD1DRD5DRD3RAD52
SCHEMBL910848 1.00 DRD2 (1.00) DRD2DRD1DRD5DRD3RAD52
SCHEMBL30473250 0.96 DRD2 (1.00) DRD2DRD1DRD5DRD3RAD52
SCHEMBL14703834 0.96 DRD1 (1.00) DRD2DRD1DRD5DRD3RAD52
SCHEMBL14703833 0.96 DRD1 (1.00) DRD2DRD1DRD5DRD3RAD52
Coreximine SCHEMBL30473249 0.96 DRD1 (1.00) DRD2DRD1DRD5DRD3RAD52
SCHEMBL14703870 0.96 DRD1 (1.00) DRD2DRD1DRD5DRD3RAD52

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220387403-A1 COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATING NASH, NAFLD, AND OBESITY CVI PHARMACEUTICALS LIMITED (KY) 2022-12-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220387403-A1 COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATING NASH, NAFLD, AND OBESITY LIPC, FABP1, CPT1A DRD2 4557/4885DRD1 4727/4885DRD5 4696/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.