SCHEMBL12345943

SCHEMBL12345943

COc1ccc(C(c2ccccc2)c2ccc(OC(=O)c3cccc(C(C)=O)c3)cc2C)c(C)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 8/20 0.47
▸ ESR1 P03372 1/20 0.46
▸ ESR2 Q92731 1/20 0.46
▸ MAPT P10636 6/20 0.44
▸ ALDH1A1 P00352 3/20 0.44
▸ KDM4E B2RXH2 2/20 0.44
▸ POLB P06746 2/20 0.44
▸ MEN1 O00255 5/20 0.44
▸ CASP3 P42574 1/20 0.44
▸ SENP8 Q96LD8 1/20 0.44
▸ SENP7 Q9BQF6 1/20 0.44
▸ SENP6 Q9GZR1 1/20 0.44
▸ SMN1; SMN2 Q16637 2/20 0.43
▸ NPC1 O15118 2/20 0.43
▸ CYP1A2 P05177 1/20 0.43
▸ CYP3A4 P08684 1/20 0.43
▸ CYP2C9 P11712 1/20 0.43
▸ CYP2C19 P33261 1/20 0.43
▸ TDP1 Q9NUW8 3/20 0.41
▸ GAA P10253 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL141628 0.85 CA1 (0.47) KMT2AMAPTALDH1A1KDM4EPOLB
SCHEMBL12762434 0.83 MAPT (0.52) KMT2AESR1ESR2MAPTALDH1A1
SCHEMBL14802303 0.81 MEN1 (0.40) KMT2AMAPTALDH1A1MEN1TDP1
SCHEMBL14579677 0.78 KMT2A (0.67) KMT2AESR1ESR2MAPTALDH1A1
SCHEMBL17018619 0.78 ESR1 (0.68) KMT2AESR1ESR2MAPTALDH1A1
SCHEMBL139343 0.77 ESR1 (0.48) KMT2AESR1ESR2MAPTALDH1A1
SCHEMBL13258485 0.76 ESR1 (0.52) KMT2AESR1ESR2MAPTKDM4E
SCHEMBL11758692 0.76 ESR1 (0.74) KMT2AESR1ESR2ALDH1A1MEN1
SCHEMBL10022910 0.76 KMT2A (0.56) KMT2AESR1ESR2MAPTALDH1A1
SCHEMBL14579678 0.76 KMT2A (0.71) KMT2AESR1ESR2MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180024449-A1 PHOTORECEPTOR FOR ELECTROPHOTOGRAPHY, METHOD FOR MANUFACTURING THE SAME, AND ELECTROPHOTOGRAPHIC DEVICE FUJI ELECTRIC CO., LTD. (JP) 2018-01-25 — — US disclosed
US-9442400-B2 Electrophotographic photoreceptor including a copolymer polyarylate resin, production method therefor, electrophotographic device including the photoreceptor, and production method for the copolymer polyarylate resin FUJI ELECTRIC CO., LTD. (JP) 2016-09-13 — — US disclosed
US-20150079510-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PRODUCTION METHOD THEREFOR, ELECTROPHOTOGRAPHIC DEVICE, AND PRODUCTION METHOD FOR COPOLYMER POLYARYLATE RESIN FUJI ELECTRIC CO., LTD. (JP) 2015-03-19 — — US disclosed
US-8404414-B2 Electrophotographic photoconductor and manufacturing method thereof FUJI ELECTRIC CO., LTD. (JP) 2013-03-26 — — US disclosed
US-20110189603-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR AND MANUFACTURING METHOD THEREOF FUJI ELECTRIC SYSTEMS CO., LTD. (JP) 2011-08-04 — — US disclosed
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