SCHEMBL141628

SCHEMBL141628

COC(=O)c1ccc(C(=O)Oc2ccc(C(c3ccccc3)c3ccc(OC)cc3C)c(C)c2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CA1 P00915 1/20 0.47
▸ CA2 P00918 1/20 0.47
▸ KMT2A Q03164 6/20 0.45
▸ MAPT P10636 7/20 0.44
▸ GAA P10253 3/20 0.44
▸ NPSR1 Q6W5P4 1/20 0.44
▸ RAB9A P51151 3/20 0.43
▸ NPC1 O15118 3/20 0.43
▸ MEN1 O00255 3/20 0.43
▸ POLB P06746 3/20 0.43
▸ PPARA Q07869 1/20 0.43
▸ SMN1; SMN2 Q16637 2/20 0.42
▸ KDM4E B2RXH2 2/20 0.42
▸ CYP1A2 P05177 1/20 0.42
▸ CYP3A4 P08684 1/20 0.42
▸ CYP2C9 P11712 1/20 0.42
▸ CYP2C19 P33261 1/20 0.42
▸ ALDH1A1 P00352 2/20 0.42
▸ TSHR P16473 1/20 0.42
▸ PRSS1 P07477 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12345943 0.85 KMT2A (0.47) KMT2AMAPTGAARAB9ANPC1
SCHEMBL14802303 0.81 MEN1 (0.40) KMT2AMAPTGAARAB9AMEN1
SCHEMBL12345942 0.75 EGFR (0.39) KMT2AMAPTRAB9ANPC1MEN1
SCHEMBL11135999 0.75 TSHR (0.52) CA1CA2KMT2AMAPTGAA
SCHEMBL13030392 0.74 TDP1 (0.51) KMT2AMAPTGAANPSR1RAB9A
SCHEMBL14580076 0.74 MAPT (0.57) KMT2AMAPTGAANPSR1RAB9A
SCHEMBL16429577 0.73 KMT2A (0.56) KMT2AMAPTGAARAB9ANPC1
SCHEMBL6274207 0.73 TSHR (0.73) CA1CA2KMT2AMAPTRAB9A
SCHEMBL12762423 0.72 MAPT (0.55) CA1CA2KMT2AMAPTGAA
SCHEMBL13612569 0.72 KMT2A (0.77) KMT2AMAPTMEN1POLBSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180024449-A1 PHOTORECEPTOR FOR ELECTROPHOTOGRAPHY, METHOD FOR MANUFACTURING THE SAME, AND ELECTROPHOTOGRAPHIC DEVICE FUJI ELECTRIC CO., LTD. (JP) 2018-01-25 — — US disclosed
US-9442400-B2 Electrophotographic photoreceptor including a copolymer polyarylate resin, production method therefor, electrophotographic device including the photoreceptor, and production method for the copolymer polyarylate resin FUJI ELECTRIC CO., LTD. (JP) 2016-09-13 — — US disclosed
US-20150079510-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PRODUCTION METHOD THEREFOR, ELECTROPHOTOGRAPHIC DEVICE, AND PRODUCTION METHOD FOR COPOLYMER POLYARYLATE RESIN FUJI ELECTRIC CO., LTD. (JP) 2015-03-19 — — US disclosed
US-8404414-B2 Electrophotographic photoconductor and manufacturing method thereof FUJI ELECTRIC CO., LTD. (JP) 2013-03-26 — — US disclosed
US-20120058422-A1 PHOTORECEPTOR FOR ELECTROPHOTOGRAPHY, PROCESS FOR PRODUCING THE SAME, AND ELECTROPHOTOGRAPHIC APPARATUS FUJI ELECTRIC CO., LTD (JP) 2012-03-08 — — US disclosed
US-20110189603-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR AND MANUFACTURING METHOD THEREOF FUJI ELECTRIC SYSTEMS CO., LTD. (JP) 2011-08-04 — — US disclosed
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